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Mohammed T. Abou-Saleh

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DISTINGUISHING DEPRESSION FROM DEMENTIA 301clinical information gathered ‘‘at the bedside’’ from the patientand his/her family. Various screening instruments and routinelaboratory studies can contribute useful additional information tothe clinician. More advanced studies, such as formal neuropsychologicaltesting, EEG, neuroimaging and genetic testing, canbe helpful in selected patients. In every case, the clinician mustkeep in mind the high concurrence rate of dementia anddepression, the increasing evidence that geriatric depression maybe a prodrome of dementia, as well as the research that points toshared etiologies of dementia and geriatric depression, and thusavoid taking a strict either/or approach.REFERENCES1. Evans DA, Funkenstein HH, Albert MS et al. Prevalence ofAlzheimer’s disease in a community population of older persons:higher than previously reported. J Am Med Assoc 1989; 262: 2551–6.2. Geldmacher DS, Whitehouse PJ. Differential diagnosis ofAlzheimer’s disease. 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