DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC ...

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OUT+5V_ISOC122uF3284+-IC1A1OPA2130+2.5VLocal AnalogGro undNotes:Components marked * must be matchedwithin 0.5%.1516IC 2BMAX39214+5V_ISOIIC 2CMAX392C233nF*R422.1K*R8*C515nFR51MR656.231827IC3INA1286R722.1K109C433nF11654-+8R344.2KIC1BOPA2130722.1K*C715nF6IC2DMAX3923IC 2AMAX392135R91M4 54+2.5V7 82 1IBLANKFigure 2.40 This intracardiac electrogram signal amplifier enables detection of evoked-response events from the heart soon after the deliveryof pacing or defibrillation pulses. A digital BLANK command is supplied just before the stimulus pulse is delivered to the heart. Thiscommand shorts the inputs of the instrumentation amplifier and changes the configuration of IC1B to an amplifier with a gain of zero.Recovery occurs within a few milliseconds after the blanking signal is released.R11MR21M*C33.3nF*C63.3nF+IN-IN94
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DESIGN AND DEVELOPMENTOF MEDICAL EL
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Copyright © 2005 by John Wiley & S
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CONTENTSPREFACEDISCLAIMERABOUT THE
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xPREFACEThe book addresses the prac
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DISCLAIMERThe projects in this book
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ABOUT THE AUTHORSDavid Prutchi is V
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2 BIOPOTENTIAL AMPLIFIERSGainG70.7%
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4 BIOPOTENTIAL AMPLIFIERSVolumeCond
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6 BIOPOTENTIAL AMPLIFIERSWarning! T
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8 BIOPOTENTIAL AMPLIFIERSIfRf-VccRi
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10 BIOPOTENTIAL AMPLIFIERSFigure 1.
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12 BIOPOTENTIAL AMPLIFIERSof the sk
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14 BIOPOTENTIAL AMPLIFIERScontamina
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20 BIOPOTENTIAL AMPLIFIERSA way of
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22 BIOPOTENTIAL AMPLIFIERSskin- ele
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26 BIOPOTENTIAL AMPLIFIERSOscillosc
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28 BIOPOTENTIAL AMPLIFIERS+15VV 132
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X1KX100X10JP2Sense3 2 13 2 14 5 6JP
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32 BIOPOTENTIAL AMPLIFIERSgenerator
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36 BIOPOTENTIAL AMPLIFIERSresults i
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38 BIOPOTENTIAL AMPLIFIERSUsing off
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42 BANDPASS SELECTION FOR BIOPOTENT
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5V_ISOIR25.1MR35.1MIR11M2374 8-+65V
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62Figure 2.14 State-variable filter
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64Figure 2.16 Since the cutoff freq
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66Figure 2.17 PSpice simulation res
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Page 222: REFERENCES 95IC2A and IC2D. At the
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Page 256: 112Figure 3.8 The simplest form of
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120 DESIGN OF SAFE MEDICAL DEVICE P
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KELVINPROBEToDVMBT21.5V "D" CellF11
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PatientConnectionsPatientConnection
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MeasuringDeviceSelectorPatientConne
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15VAC115VAC2ISO 125VACDUT GND SENSE
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+12V+15V+7V-15V-7V+ C176.8uF+ C166.
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117VACHOTNEUTRAL12MAIN ACPOWERSW2SW
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TRIPD61N4148BufferR220k 1.0%Precisi
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148 ELECTROMAGNETIC COMPATIBILITY A
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164Figure 4.11 The intermediate-fre
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Metal BoxHot(Black)L150uHC11.0uF 40
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5SIGNAL CONDITIONING, DATA ACQUISIT
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UNIVERSAL SENSOR INTERFACE 207Figur
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Figure 5.3 Schematic diagram of the
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UNIVERSAL SENSOR INTERFACE 211As co
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UNIVERSAL SENSOR INTERFACE 213dat
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UNIVERSAL SENSOR INTERFACE 215TABLE
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UNIVERSAL SENSOR INTERFACE 217For d
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UNIVERSAL SENSOR INTERFACE 219Figur
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UNIVERSAL SENSOR INTERFACE 22111421
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UNIVERSAL SENSOR INTERFACE 223TO J2
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SAMPLING RATE AND THE NYQUIST THEOR
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FREE DATA ACQUISITION CARD IN YOUR
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OUTOUTGNDTOSOUNDCARDR1C110kR21000.1
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FREE DATA ACQUISITION CARD IN YOUR
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SPECTRAL ANALYSIS 233TABLE 5.4 Some
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SPECTRAL ANALYSIS 235In most instan
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w n x n e 2πjf n ∆t X( f ) ∆t
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SPECTRAL ANALYSIS 239High-Resolutio
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SPECTRAL ANALYSIS 241Figure 5.19 Po
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SPECTRAL ANALYSIS 243order, but an
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SPECTRAL ANALYSIS 245Figure 5.21 A
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REFERENCES 247apart over the biceps
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250 SIGNAL SOURCES FOR SIMULATION,
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OUTPUTJ2SMBR10502WJP1JUMPER 3JP2JUM
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T112VAC 1AD11N4005D31N4005+ C45+220
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C791uFR112Z_SIG_OUTZ Amplitude~0-50
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294Figure 6.31 A potentiostat-galva
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7STIMULATION OF EXCITABLE TISSUESAn
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STIMULATION OF EXCITABLE TISSUES 30
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EXTRACELLULAR STIMULATION 309membra
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CLINICAL USES OF ELECTRICAL STIMULA
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9. Control of Parkinsonian tremor.
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TABLE 7.1(Continued)CLINICAL USES O
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DIRECT STIMULATION OF NERVE AND MUS
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ELECTRODE 1ELECTRODE 2I_OUTR3+15V_S
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WAVEFORM:CLOSED = MONOPHASICOPEN =
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BT1 BT2 BT3 BT41.5V1.5V1.5V1.5VSW1P
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ELECTRODE 3BODY PARTTO BESTIMULATED
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• Cardiac demand pacemakers that
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MAGNETIC STIMULATION 347trast, a ma
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SCR1ST330S16P0L1COILEXTREME DANGER!
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MAGNETIC STIMULATION 351• TOFF: t
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MAGNETIC STIMULATION 353+ -d/dtCOIL
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MAGNETIC STIMULATION 355tube cap. A
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OTHER CLINICAL APPLICATIONS OF ELEC
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Hodgkin, A. L., and A. F. Huxley, A
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8CARDIAC PACING AND DEFIBRILLATIONW
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BRADYARRHYTHMIAS 371As a result, on
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THE FIRST PACEMAKERS 373designed in
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Figure 8.4 The output of a PSpice s
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THE FIRST PACEMAKERS 377V SenseA Se
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Pacing Mode This parameter selects
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EXTERNAL VVI PACEMAKER 381EXTERNAL
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Figure 8.11 presents the schematic
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VDDV+AnodeACTI VE_DISCHARGEQ1BSS84R
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EXTERNAL VVI PACEMAKER 387TimeStamp
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EXTERNAL VVI PACEMAKER 389}}default
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SOFTWARE TESTING 391Of course, safe
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IMPEDANCE TECHNIQUE 393contraction)
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IMPEDANCE TECHNIQUE 395
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IMPEDANCE TECHNIQUE 397C110.1uFR205
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DEMOD_OUT+15Viso-15VisoINPUTJ5SMC39
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INTRACARDIAC IMPEDANCE SENSOR 401Le
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INTRACARDIAC IMPEDANCE SENSOR 403At
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INTRACARDIAC IMPEDANCE SENSOR 405Fi
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VENTRICULAR TACHYARRHYTHMIAS 407Tim
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1.61.41.2Output Voltage10.80.60.4DV
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VENTRICULAR TACHYARRHYTHMIAS 411Imp
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DEFIBRILLATION 413stimulus waveform
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SW5Safety InterlockF12AF20.25ASW1Po
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SHOCK BOX PROTOTYPE 417defibrillati
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SHOCK BOX PROTOTYPE 419Figure 8.34
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Figure 8.36 Interconnection diagram
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SHOCK BOX PROTOTYPE 423In operation
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SHOCK BOX PROTOTYPE 425markets and
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Figure 8.40 A H-bridge switch confi
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SHOCK BOX PROTOTYPE 429V_CAP_OUTR56
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SHOCK BOX PROTOTYPE 431onboard the
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SHOCK BOX PROTOTYPE 433+12_VBATC791
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SHOCK BOX PROTOTYPE 435value by the
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CARDIAC FIBRILLATOR 4373. Every 1 s
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CONCLUDING REMARKS 439+9VS1R1IC15CO
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EPILOGUEOut of clutter, find simpli
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PATH THROUGH THE FDA 443intended us
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the industry is undergoing profound
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APPENDIX ASOURCES FOR MATERIALS AND
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SOURCES FOR MATERIALS AND COMPONENT
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APPENDIX BFTP SITE CONTENTftp://ftp
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FTP SITE CONTENT 453• LPT8FAST.BA
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FTP SITE CONTENT 455Folder: Redistr
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458 INDEXCentro de Construccion de
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460 INDEXPacemaker(s) (Continued)pu
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