DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC ...

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FTP SITE CONTENT 455Folder: Redistributed Freeware• SoundArb v1.02 (SASETUP.EXE freeware for Windows 9x, NT) by David ShermanEngineering Co.Software for Chapter 7: Stimulation of Excitable TissueFolder: Hodgkin–Huxley• HODGKINHUXLEY.M is a Matlab program that simulates the response of a giantsquid axon to an electrical stimulus. ALPHA_H.M, ALPHA_M.M, ALPHA_ N.M,BETA_H.M, BETA_M.M and BETA_N.M are Matlab functions that calculate therate constants for the Hodgkin–Huxley model.Folder: Redistributed Freeware• Finite Element Methods for Magnetics v3.1 (FEEM_SETUP.EXE freeware forWindows 9x) by David Meeker.• WireTronic wire information software (WTSETUP.EXE freeware for Windows 9x)by WireTronic, Inc.• VirtualCV v1.0 cyclic voltammetry simulator (VTLCV10.ZIP freeware for Windows9x) by Andre Laouenan.• Beat-tone generation (BEATINBRAIN.EXE, freeware for Windows 9x, 2000, NT)by the Physics Lab of Rutgers University. This program generates two sine waves ofdifferent frequencies through the left and right sound card. Can be used with isolatedhigh-voltage output stages for interferential muscle stimulation.Software for Chapter 8: Cardiac Pacemakers and DefibrillatorsFolder: VVI• VVI.ZIP implements a simple VVI state machine that disregards the VOO mode. Thisis the program that was discussed above.• VVI WITH EMBEDDED VOO.ZIP implements a VVI state machine that can beplaced in VOO mode by disregarding sensed events. The state machine is identical tothe one implemented in VVI.ZIP, but the EnableSense routine enables or disablessensing depending on the desired state.• VVI VOO WITH VOO STATE.ZIP is a VVI state machine in which the VOO state isimplemented through a new state during which there is no sensing.Folder: DOCD• This file contains the PIC firmware for the DOCD Impedance Sensor (DOCD.ASM).Folder: Shock-Box Firmware and Control Software• This file contains the firmware for the defibrillation shock-box PICs and the VBControl software for the defibrillation shock box (SHOCKBOX.ZIP).
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DESIGN AND DEVELOPMENTOF MEDICAL EL
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Copyright © 2005 by John Wiley & S
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CONTENTSPREFACEDISCLAIMERABOUT THE
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xPREFACEThe book addresses the prac
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DISCLAIMERThe projects in this book
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ABOUT THE AUTHORSDavid Prutchi is V
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2 BIOPOTENTIAL AMPLIFIERSGainG70.7%
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4 BIOPOTENTIAL AMPLIFIERSVolumeCond
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6 BIOPOTENTIAL AMPLIFIERSWarning! T
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8 BIOPOTENTIAL AMPLIFIERSIfRf-VccRi
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10 BIOPOTENTIAL AMPLIFIERSFigure 1.
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12 BIOPOTENTIAL AMPLIFIERSof the sk
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14 BIOPOTENTIAL AMPLIFIERScontamina
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20 BIOPOTENTIAL AMPLIFIERSA way of
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22 BIOPOTENTIAL AMPLIFIERSskin- ele
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26 BIOPOTENTIAL AMPLIFIERSOscillosc
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28 BIOPOTENTIAL AMPLIFIERS+15VV 132
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X1KX100X10JP2Sense3 2 13 2 14 5 6JP
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32 BIOPOTENTIAL AMPLIFIERSgenerator
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36 BIOPOTENTIAL AMPLIFIERSresults i
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38 BIOPOTENTIAL AMPLIFIERSUsing off
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42 BANDPASS SELECTION FOR BIOPOTENT
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5V_ISOIR25.1MR35.1MIR11M2374 8-+65V
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62Figure 2.14 State-variable filter
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64Figure 2.16 Since the cutoff freq
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66Figure 2.17 PSpice simulation res
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OUTOutputOut GND6R42kIC 1UAF42 8Hig
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-OUTOUTGNDININPUTINGND11R5100k1213+
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86Figure 2.35 The slew-rate limiter
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J3OUTPUTBNC2CR81.05KIC 2C406654 3LP
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IC5DCD4093B11CDisplay_InAD131N41484
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OUT+5V_ISOC122uF3284+-IC1A1OPA2130+
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3DESIGN OF SAFE MEDICALDEVICE PROTO
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STANDARDS FOR PROTECTION AGAINST EL
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LEAKAGE CURRENTS 1011. Ground leaka
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Figure 3.2 A universal differential
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DESIGN EXAMPLE: ISOLATED DIFFERENTI
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-15VC6+15VC5.01uFIC2.01uF UA741 -15
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ANALOG SIGNAL ISOLATION USING OPTIC
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LINEAR ANALOG ISOLATION USING OPTOI
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LINEAR ANALOG ISOLATION USING OPTOI
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NON ISO.POWERSignalOutputJP312ISO.P
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ISOLATEDPOWERINPUTJ4ISOLATED SIDENO
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DIGITAL ALTERNATIVE TO SIGNAL ISOLA
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SOFTWARE FOR THE ISOLATED A/D 121LP
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POWER SUPPLIES 123Figure 3.17 The n
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ADDITIONAL PROTECTION 125In additio
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TESTING FOR COMPLIANCE 127designed
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TESTING FOR COMPLIANCE 129Voltage-M
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TESTING FOR COMPLIANCE 131The frequ
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SelectorSelectorPatientConnectionsP
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+V_LCD-V_LCDC110.01uFR1462kR1362kC6
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ISOLATED 125 VACAC BALANCE125VAC TO
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TABLE 3.3 Normal and Fault Conditio
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TESTING FOR COMPLIANCE 141TABLE 3.4
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TESTING FOR COMPLIANCE 143HI-POTHV
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TESTING FOR COMPLIANCE 145that diel
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4ELECTROMAGNETIC COMPATIBILITYAND M
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RADIATED EMISSIONS FROM DIGITAL CIR
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RADIATED EMISSIONS FROM DIGITAL CIR
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+24VISOC6100nFIsoC12100nFIso15IC1+V
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ELECTROMAGNETIC FIELDS 155TABLE 4.3
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ELECTROMAGNETIC FIELDS 157andIlH(A/
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PROBING E- AND H-FIELDS IN THE NEAR
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BARE-BONES SPECTRUM ANALYZER 161mag
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45MHz_IFR813R982L2L1LOFREQUENCYADJU
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single-chip IF processor, takes car
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CONDUCTED EMISSIONS 167J2BNC1220MHz
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CONDUCTED EMISSIONS 169LISN40 cmLIS
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SUSCEPTIBILITY 171TABLE 4.4EN-55011
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SUSCEPTIBILITY 173The human body mo
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SUSCEPTIBILITY 175Gas delivery tube
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SUSCEPTIBILITY 177the user that the
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SUSCEPTIBILITY 179Figure 4.22 A pro
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SUSCEPTIBILITY 181+12VSW 1*= Heatsi
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SUSCEPTIBILITY 183Ground PlaneContr
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J2To D evi ceUnd er Te stAC Power P
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SUSCEPTIBILITY 187mode after a prol
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GOOD DESIGN PRACTICES, REMEDIES, AN
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REFERENCES 203REFERENCESDash, G., a
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206 SIGNAL CONDITIONING, DATA ACQUI
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SCLKDOUT*CSMUXD0MUXD1MUXD2ANALOG TO
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210Figure 5.4 Timing diagram for th
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TO J1UNIVERSALSENSORINTERFACECONNEC
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+C110uFC20.1uFR1100k+12VR2C30.01uFI
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6SIGNAL SOURCES FOR SIMULATION,TEST
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OUTPUTSW1C11uF,25VC30.1uF++15V-15VC
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15+12V+12V147147TRIGGERCLOCKADJUSTC
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DIGITAL GENERATION OF ANALOG WAVEFO
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DIGITAL GENERATION OF ANALOG WAVEFO
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ARB BASICS 259TABLE 6.2 Input Lines
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ARB BASICS 261If more than sufficie
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ARB BASICS 263Figure 6.11 The addre
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D[0:31]D[0:31]+5VSW2R4510kJ3BNCCLK_
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CLK_LOCALC330.022uFC342200pFSW3200k
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ARB BASICS 269Finally, a word of ca
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ARB BASICS 271complex waveform can
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ARB BASICS 273design package such a
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OUTOUTPUTOUTGNDIC1BTL0847-5V+5V+5V+
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RESPONSIVE SIMULATORS 277Figure 6.1
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Figure 6.21 Right-atrial and right-
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+15VCLKDINIC31LTC1451VCCVOUT+5VC390
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RESPONSIVE SIMULATORS 283IC40B scal
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Figure 6.26 This bar graph display
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RESPONSIVE SIMULATORS 287A EventDet
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RESPONSIVE SIMULATORS 289relatively
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Figure 6.30 A torso simulator model
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Experimental validation studies for
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RESPONSIVE SIMULATORS 295One Telede
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inner surface. Their heart source m
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VERY REALISTIC PHYSIOLOGICAL SIGNAL
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..--R+-111698134TO A/DIN1IN2IN3IN4V
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REFERENCES 303We believe that exper
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306 STIMULATION OF EXCITABLE TISSUE
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FAULT:COMPLIANCELIMITD1RED LEDIC2BP
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CURRENTTOOSCILLOSCOPECHANNEL 2"Y" I
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PULSER9250kR148.2kEXTERNAL TRIGGERS
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I1TR280IR_TISSUE100k+ -d/dt d/dt10u
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I(R_COIL)V(dIdt)V(CAPACITOR_BANK)I(
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370 CARDIAC PACING AND DEFIBRILLATI
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VDDR211MVDDR20750KC6RefractoryPerio
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SENSING INVDDR45.1MC347NFD2HSMS2802
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DIFFERENTIALOFFSETNULLINGR3510KR371
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IMPED_OUTGND PWR+ C3522uF+ C3922uFL
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410Figure 8.30 Intracardiac impedan
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Q17IRF9530+24V_SW+15V_NON_ISOGND NO
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Page 896: 432 CARDIAC PACING AND DEFIBRILLATI
Page 900: 434Figure 8.46 A lead impedance sen
Page 916: 442 EPILOGUEmagnitude of the issue,
Page 920: 444 EPILOGUEAll data supplied by th
Page 924: 446 EPILOGUEby many factors: What d
Page 928: 448 APPENDIX AChomericswww.chomeric
Page 932: 450 APPENDIX ARadio Shackwww.radios
Page 936: 452 APPENDIX Bthe authors or the pu
Page 940: 454 APPENDIX BAudio Oscilloscopes f
Page 948: 458 INDEXCentro de Construccion de
Page 952: 460 INDEXPacemaker(s) (Continued)pu
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