DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC ...

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SENSING INVDDR45.1MC347NFD2HSMS2802 1 2VDDR720KR176.8K3R185.1KC4100NFR882KC522NFR193.9KR647KR947K32R115.1M7+6- IC1 UPC42504 8R1215MR510-15M327UPC4250+- IC24 86R1315M327UPC4250+- IC34 8HSMS28246R1415MD3R101MSW11RSW6SENSITIVITYSELECTORFigure 8.11 The sense amplifier circuit detects ventricular electrogram signals through electrodes attached to the ventricle. Signals areattenuated by the voltage divider formed by resistor R7 and one of the resistors among R15, R16, R17, R18, or R19. Selection of the senseamplifier sensitivity is through switch SW1. Signals within band 88 to 100 Hz are then amplified by IC1. Comparators IC2 and IC3 detectthreshold crossings by the signal. Sense events are sent to microcontroller IC4 when either comparator is activated.R1610KV+V-R1520K384
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DESIGN AND DEVELOPMENTOF MEDICAL EL
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Copyright © 2005 by John Wiley & S
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CONTENTSPREFACEDISCLAIMERABOUT THE
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xPREFACEThe book addresses the prac
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DISCLAIMERThe projects in this book
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ABOUT THE AUTHORSDavid Prutchi is V
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2 BIOPOTENTIAL AMPLIFIERSGainG70.7%
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4 BIOPOTENTIAL AMPLIFIERSVolumeCond
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6 BIOPOTENTIAL AMPLIFIERSWarning! T
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8 BIOPOTENTIAL AMPLIFIERSIfRf-VccRi
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10 BIOPOTENTIAL AMPLIFIERSFigure 1.
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12 BIOPOTENTIAL AMPLIFIERSof the sk
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14 BIOPOTENTIAL AMPLIFIERScontamina
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20 BIOPOTENTIAL AMPLIFIERSA way of
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22 BIOPOTENTIAL AMPLIFIERSskin- ele
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26 BIOPOTENTIAL AMPLIFIERSOscillosc
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28 BIOPOTENTIAL AMPLIFIERS+15VV 132
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X1KX100X10JP2Sense3 2 13 2 14 5 6JP
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32 BIOPOTENTIAL AMPLIFIERSgenerator
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36 BIOPOTENTIAL AMPLIFIERSresults i
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38 BIOPOTENTIAL AMPLIFIERSUsing off
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42 BANDPASS SELECTION FOR BIOPOTENT
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5V_ISOIR25.1MR35.1MIR11M2374 8-+65V
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62Figure 2.14 State-variable filter
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64Figure 2.16 Since the cutoff freq
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66Figure 2.17 PSpice simulation res
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OUTOutputOut GND6R42kIC 1UAF42 8Hig
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-OUTOUTGNDININPUTINGND11R5100k1213+
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86Figure 2.35 The slew-rate limiter
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J3OUTPUTBNC2CR81.05KIC 2C406654 3LP
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IC5DCD4093B11CDisplay_InAD131N41484
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OUT+5V_ISOC122uF3284+-IC1A1OPA2130+
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3DESIGN OF SAFE MEDICALDEVICE PROTO
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STANDARDS FOR PROTECTION AGAINST EL
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LEAKAGE CURRENTS 1011. Ground leaka
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Figure 3.2 A universal differential
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DESIGN EXAMPLE: ISOLATED DIFFERENTI
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-15VC6+15VC5.01uFIC2.01uF UA741 -15
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ANALOG SIGNAL ISOLATION USING OPTIC
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LINEAR ANALOG ISOLATION USING OPTOI
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LINEAR ANALOG ISOLATION USING OPTOI
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NON ISO.POWERSignalOutputJP312ISO.P
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ISOLATEDPOWERINPUTJ4ISOLATED SIDENO
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DIGITAL ALTERNATIVE TO SIGNAL ISOLA
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SOFTWARE FOR THE ISOLATED A/D 121LP
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POWER SUPPLIES 123Figure 3.17 The n
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ADDITIONAL PROTECTION 125In additio
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TESTING FOR COMPLIANCE 127designed
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TESTING FOR COMPLIANCE 129Voltage-M
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TESTING FOR COMPLIANCE 131The frequ
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SelectorSelectorPatientConnectionsP
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+V_LCD-V_LCDC110.01uFR1462kR1362kC6
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ISOLATED 125 VACAC BALANCE125VAC TO
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TABLE 3.3 Normal and Fault Conditio
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TESTING FOR COMPLIANCE 141TABLE 3.4
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TESTING FOR COMPLIANCE 143HI-POTHV
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TESTING FOR COMPLIANCE 145that diel
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4ELECTROMAGNETIC COMPATIBILITYAND M
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RADIATED EMISSIONS FROM DIGITAL CIR
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RADIATED EMISSIONS FROM DIGITAL CIR
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+24VISOC6100nFIsoC12100nFIso15IC1+V
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ELECTROMAGNETIC FIELDS 155TABLE 4.3
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ELECTROMAGNETIC FIELDS 157andIlH(A/
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PROBING E- AND H-FIELDS IN THE NEAR
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BARE-BONES SPECTRUM ANALYZER 161mag
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45MHz_IFR813R982L2L1LOFREQUENCYADJU
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single-chip IF processor, takes car
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CONDUCTED EMISSIONS 167J2BNC1220MHz
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CONDUCTED EMISSIONS 169LISN40 cmLIS
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SUSCEPTIBILITY 171TABLE 4.4EN-55011
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SUSCEPTIBILITY 173The human body mo
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SUSCEPTIBILITY 175Gas delivery tube
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SUSCEPTIBILITY 177the user that the
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SUSCEPTIBILITY 179Figure 4.22 A pro
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SUSCEPTIBILITY 181+12VSW 1*= Heatsi
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SUSCEPTIBILITY 183Ground PlaneContr
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J2To D evi ceUnd er Te stAC Power P
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SUSCEPTIBILITY 187mode after a prol
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GOOD DESIGN PRACTICES, REMEDIES, AN
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REFERENCES 203REFERENCESDash, G., a
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206 SIGNAL CONDITIONING, DATA ACQUI
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SCLKDOUT*CSMUXD0MUXD1MUXD2ANALOG TO
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210Figure 5.4 Timing diagram for th
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TO J1UNIVERSALSENSORINTERFACECONNEC
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+C110uFC20.1uFR1100k+12VR2C30.01uFI
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6SIGNAL SOURCES FOR SIMULATION,TEST
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OUTPUTSW1C11uF,25VC30.1uF++15V-15VC
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15+12V+12V147147TRIGGERCLOCKADJUSTC
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DIGITAL GENERATION OF ANALOG WAVEFO
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DIGITAL GENERATION OF ANALOG WAVEFO
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ARB BASICS 259TABLE 6.2 Input Lines
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ARB BASICS 261If more than sufficie
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ARB BASICS 263Figure 6.11 The addre
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D[0:31]D[0:31]+5VSW2R4510kJ3BNCCLK_
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CLK_LOCALC330.022uFC342200pFSW3200k
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ARB BASICS 269Finally, a word of ca
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ARB BASICS 271complex waveform can
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ARB BASICS 273design package such a
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OUTOUTPUTOUTGNDIC1BTL0847-5V+5V+5V+
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RESPONSIVE SIMULATORS 277Figure 6.1
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Figure 6.21 Right-atrial and right-
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+15VCLKDINIC31LTC1451VCCVOUT+5VC390
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RESPONSIVE SIMULATORS 283IC40B scal
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Figure 6.26 This bar graph display
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RESPONSIVE SIMULATORS 287A EventDet
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RESPONSIVE SIMULATORS 289relatively
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Figure 6.30 A torso simulator model
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Experimental validation studies for
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RESPONSIVE SIMULATORS 295One Telede
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inner surface. Their heart source m
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VERY REALISTIC PHYSIOLOGICAL SIGNAL
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..--R+-111698134TO A/DIN1IN2IN3IN4V
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REFERENCES 303We believe that exper
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306 STIMULATION OF EXCITABLE TISSUE
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FAULT:COMPLIANCELIMITD1RED LEDIC2BP
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CURRENTTOOSCILLOSCOPECHANNEL 2"Y" I
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PULSER9250kR148.2kEXTERNAL TRIGGERS
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I1TR280IR_TISSUE100k+ -d/dt d/dt10u
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I(R_COIL)V(dIdt)V(CAPACITOR_BANK)I(
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Page 748: 358 STIMULATION OF EXCITABLE TISSUE
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Page 806: EXTERNAL VVI PACEMAKER 387TimeStamp
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Page 814: SOFTWARE TESTING 391Of course, safe
Page 818: IMPEDANCE TECHNIQUE 393contraction)
Page 822: IMPEDANCE TECHNIQUE 395
Page 826: IMPEDANCE TECHNIQUE 397C110.1uFR205
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Page 834: INTRACARDIAC IMPEDANCE SENSOR 401Le
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Page 842: INTRACARDIAC IMPEDANCE SENSOR 405Fi
Page 846: VENTRICULAR TACHYARRHYTHMIAS 407Tim
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1.61.41.2Output Voltage10.80.60.4DV
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VENTRICULAR TACHYARRHYTHMIAS 411Imp
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DEFIBRILLATION 413stimulus waveform
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SW5Safety InterlockF12AF20.25ASW1Po
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SHOCK BOX PROTOTYPE 417defibrillati
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SHOCK BOX PROTOTYPE 419Figure 8.34
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Figure 8.36 Interconnection diagram
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SHOCK BOX PROTOTYPE 423In operation
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SHOCK BOX PROTOTYPE 425markets and
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Figure 8.40 A H-bridge switch confi
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SHOCK BOX PROTOTYPE 429V_CAP_OUTR56
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SHOCK BOX PROTOTYPE 431onboard the
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SHOCK BOX PROTOTYPE 433+12_VBATC791
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SHOCK BOX PROTOTYPE 435value by the
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CARDIAC FIBRILLATOR 4373. Every 1 s
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CONCLUDING REMARKS 439+9VS1R1IC15CO
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EPILOGUEOut of clutter, find simpli
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PATH THROUGH THE FDA 443intended us
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the industry is undergoing profound
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APPENDIX ASOURCES FOR MATERIALS AND
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SOURCES FOR MATERIALS AND COMPONENT
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APPENDIX BFTP SITE CONTENTftp://ftp
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FTP SITE CONTENT 453• LPT8FAST.BA
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FTP SITE CONTENT 455Folder: Redistr
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458 INDEXCentro de Construccion de
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460 INDEXPacemaker(s) (Continued)pu
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