DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC ...

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FAULT:COMPLIANCELIMITD1RED LEDIC2BPS2501- 4I_OUTELECTRODE 1IC2DPS2501-4ELECTRODE 2+15V<strong>OF</strong>FSET NULLR1100kR350kR649.9kR422M32+-+15V84-15V1IC1ALT1013R21kC1330pFR5120Q12N4403D24 X 1N4148 BRIDGE14+-2+15V31287IC3APS2501-2IC3BPS2501-256+15VBT19 to 60V43125616151211IC2APS2501-4IC2CPS2501-434781413901GAINTRIM2kR8R94.02k56R105.1k+-847C20.1uFIC1BLT1013R75.1kQ22N3904-15VC30.1uFFigure 7.13 In this circuit for neurophysiology research, the four optocoupler transistors of the H-bridge are used to switch the polarity ofthe current source and to regulate the current delivered to the electrodes. The current delivered to the bridge is sensed by optocoupler IC3B.The current-control loop is closed via IC1A, which receives setpoint and feedback currents through IC3A and IC3B, respectively.J1V_IN 12324
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DESIGN AND DEVELOPMENTOF MEDICAL EL
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Copyright © 2005 by John Wiley & S
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CONTENTSPREFACEDISCLAIMERABOUT THE
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xPREFACEThe book addresses the prac
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DISCLAIMERThe projects in this book
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ABOUT THE AUTHORSDavid Prutchi is V
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2 BIOPOTENTIAL AMPLIFIERSGainG70.7%
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4 BIOPOTENTIAL AMPLIFIERSVolumeCond
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6 BIOPOTENTIAL AMPLIFIERSWarning! T
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8 BIOPOTENTIAL AMPLIFIERSIfRf-VccRi
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10 BIOPOTENTIAL AMPLIFIERSFigure 1.
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12 BIOPOTENTIAL AMPLIFIERSof the sk
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14 BIOPOTENTIAL AMPLIFIERScontamina
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20 BIOPOTENTIAL AMPLIFIERSA way of
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22 BIOPOTENTIAL AMPLIFIERSskin- ele
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26 BIOPOTENTIAL AMPLIFIERSOscillosc
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28 BIOPOTENTIAL AMPLIFIERS+15VV 132
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X1KX100X10JP2Sense3 2 13 2 14 5 6JP
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32 BIOPOTENTIAL AMPLIFIERSgenerator
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36 BIOPOTENTIAL AMPLIFIERSresults i
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38 BIOPOTENTIAL AMPLIFIERSUsing off
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42 BANDPASS SELECTION FOR BIOPOTENT
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5V_ISOIR25.1MR35.1MIR11M2374 8-+65V
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62Figure 2.14 State-variable filter
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64Figure 2.16 Since the cutoff freq
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66Figure 2.17 PSpice simulation res
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OUTOutputOut GND6R42kIC 1UAF42 8Hig
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-OUTOUTGNDININPUTINGND11R5100k1213+
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86Figure 2.35 The slew-rate limiter
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J3OUTPUTBNC2CR81.05KIC 2C406654 3LP
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IC5DCD4093B11CDisplay_InAD131N41484
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OUT+5V_ISOC122uF3284+-IC1A1OPA2130+
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3DESIGN OF SAFE MEDICALDEVICE PROTO
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STANDARDS FOR PROTECTION AGAINST EL
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LEAKAGE CURRENTS 1011. Ground leaka
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Figure 3.2 A universal differential
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DESIGN EXAMPLE: ISOLATED DIFFERENTI
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-15VC6+15VC5.01uFIC2.01uF UA741 -15
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ANALOG SIGNAL ISOLATION USING OPTIC
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LINEAR ANALOG ISOLATION USING OPTOI
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LINEAR ANALOG ISOLATION USING OPTOI
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NON ISO.POWERSignalOutputJP312ISO.P
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ISOLATEDPOWERINPUTJ4ISOLATED SIDENO
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DIGITAL ALTERNATIVE TO SIGNAL ISOLA
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SOFTWARE FOR THE ISOLATED A/D 121LP
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POWER SUPPLIES 123Figure 3.17 The n
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ADDITIONAL PROTECTION 125In additio
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TESTING FOR COMPLIANCE 127designed
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TESTING FOR COMPLIANCE 129Voltage-M
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TESTING FOR COMPLIANCE 131The frequ
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SelectorSelectorPatientConnectionsP
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+V_LCD-V_LCDC110.01uFR1462kR1362kC6
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ISOLATED 125 VACAC BALANCE125VAC TO
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TABLE 3.3 Normal and Fault Conditio
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TESTING FOR COMPLIANCE 141TABLE 3.4
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TESTING FOR COMPLIANCE 143HI-POTHV
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TESTING FOR COMPLIANCE 145that diel
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4ELECTROMAGNETIC COMPATIBILITYAND M
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RADIATED EMISSIONS FROM DIGITAL CIR
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RADIATED EMISSIONS FROM DIGITAL CIR
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+24VISOC6100nFIsoC12100nFIso15IC1+V
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ELECTROMAGNETIC FIELDS 155TABLE 4.3
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ELECTROMAGNETIC FIELDS 157andIlH(A/
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PROBING E- AND H-FIELDS IN THE NEAR
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BARE-BONES SPECTRUM ANALYZER 161mag
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45MHz_IFR813R982L2L1LOFREQUENCYADJU
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single-chip IF processor, takes car
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CONDUCTED EMISSIONS 167J2BNC1220MHz
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CONDUCTED EMISSIONS 169LISN40 cmLIS
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SUSCEPTIBILITY 171TABLE 4.4EN-55011
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SUSCEPTIBILITY 173The human body mo
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SUSCEPTIBILITY 175Gas delivery tube
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SUSCEPTIBILITY 177the user that the
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SUSCEPTIBILITY 179Figure 4.22 A pro
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SUSCEPTIBILITY 181+12VSW 1*= Heatsi
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SUSCEPTIBILITY 183Ground PlaneContr
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J2To D evi ceUnd er Te stAC Power P
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SUSCEPTIBILITY 187mode after a prol
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GOOD DESIGN PRACTICES, REMEDIES, AN
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REFERENCES 203REFERENCESDash, G., a
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206 SIGNAL CONDITIONING, DATA ACQUI
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SCLKDOUT*CSMUXD0MUXD1MUXD2ANALOG TO
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210Figure 5.4 Timing diagram for th
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TO J1UNIVERSALSENSORINTERFACECONNEC
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+C110uFC20.1uFR1100k+12VR2C30.01uFI
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6SIGNAL SOURCES FOR SIMULATION,TEST
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OUTPUTSW1C11uF,25VC30.1uF++15V-15VC
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15+12V+12V147147TRIGGERCLOCKADJUSTC
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DIGITAL GENERATION OF ANALOG WAVEFO
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DIGITAL GENERATION OF ANALOG WAVEFO
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ARB BASICS 259TABLE 6.2 Input Lines
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ARB BASICS 261If more than sufficie
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ARB BASICS 263Figure 6.11 The addre
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D[0:31]D[0:31]+5VSW2R4510kJ3BNCCLK_
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CLK_LOCALC330.022uFC342200pFSW3200k
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ARB BASICS 269Finally, a word of ca
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ARB BASICS 271complex waveform can
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ARB BASICS 273design package such a
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OUTOUTPUTOUTGNDIC1BTL0847-5V+5V+5V+
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RESPONSIVE SIMULATORS 277Figure 6.1
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Figure 6.21 Right-atrial and right-
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+15VCLKDINIC31LTC1451VCCVOUT+5VC390
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RESPONSIVE SIMULATORS 283IC40B scal
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Figure 6.26 This bar graph display
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RESPONSIVE SIMULATORS 287A EventDet
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RESPONSIVE SIMULATORS 289relatively
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Figure 6.30 A torso simulator model
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Experimental validation studies for
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RESPONSIVE SIMULATORS 295One Telede
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inner surface. Their heart source m
Page 630: VERY REALISTIC PHYSIOLOGICAL SIGNAL
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Page 638: REFERENCES 303We believe that exper
Page 644: 306 STIMULATION OF EXCITABLE TISSUE
Page 682: DIRECT STIMULATION OF NERVE AND MUS
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Page 718: ELECTRODE 3BODY PARTTO BESTIMULATED
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Page 726: MAGNETIC STIMULATION 347trast, a ma
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SCR1ST330S16P0L1COILEXTREME DANGER!
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MAGNETIC STIMULATION 351• TOFF: t
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MAGNETIC STIMULATION 353+ -d/dtCOIL
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MAGNETIC STIMULATION 355tube cap. A
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OTHER CLINICAL APPLICATIONS OF ELEC
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Hodgkin, A. L., and A. F. Huxley, A
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8CARDIAC PACING AND DEFIBRILLATIONW
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BRADYARRHYTHMIAS 371As a result, on
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THE FIRST PACEMAKERS 373designed in
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Figure 8.4 The output of a PSpice s
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THE FIRST PACEMAKERS 377V SenseA Se
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Pacing Mode This parameter selects
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EXTERNAL VVI PACEMAKER 381EXTERNAL
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Figure 8.11 presents the schematic
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VDDV+AnodeACTI VE_DISCHARGEQ1BSS84R
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EXTERNAL VVI PACEMAKER 387TimeStamp
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EXTERNAL VVI PACEMAKER 389}}default
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SOFTWARE TESTING 391Of course, safe
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IMPEDANCE TECHNIQUE 393contraction)
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IMPEDANCE TECHNIQUE 395
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IMPEDANCE TECHNIQUE 397C110.1uFR205
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DEMOD_OUT+15Viso-15VisoINPUTJ5SMC39
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INTRACARDIAC IMPEDANCE SENSOR 401Le
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INTRACARDIAC IMPEDANCE SENSOR 403At
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INTRACARDIAC IMPEDANCE SENSOR 405Fi
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VENTRICULAR TACHYARRHYTHMIAS 407Tim
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1.61.41.2Output Voltage10.80.60.4DV
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VENTRICULAR TACHYARRHYTHMIAS 411Imp
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DEFIBRILLATION 413stimulus waveform
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SW5Safety InterlockF12AF20.25ASW1Po
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SHOCK BOX PROTOTYPE 417defibrillati
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SHOCK BOX PROTOTYPE 419Figure 8.34
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Figure 8.36 Interconnection diagram
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SHOCK BOX PROTOTYPE 423In operation
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SHOCK BOX PROTOTYPE 425markets and
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Figure 8.40 A H-bridge switch confi
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SHOCK BOX PROTOTYPE 429V_CAP_OUTR56
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SHOCK BOX PROTOTYPE 431onboard the
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SHOCK BOX PROTOTYPE 433+12_VBATC791
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SHOCK BOX PROTOTYPE 435value by the
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CARDIAC FIBRILLATOR 4373. Every 1 s
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CONCLUDING REMARKS 439+9VS1R1IC15CO
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EPILOGUEOut of clutter, find simpli
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PATH THROUGH THE FDA 443intended us
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the industry is undergoing profound
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APPENDIX ASOURCES FOR MATERIALS AND
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SOURCES FOR MATERIALS AND COMPONENT
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APPENDIX BFTP SITE CONTENTftp://ftp
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FTP SITE CONTENT 453• LPT8FAST.BA
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FTP SITE CONTENT 455Folder: Redistr
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458 INDEXCentro de Construccion de
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460 INDEXPacemaker(s) (Continued)pu
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