DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC ...

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+12V+15V+7V-15V-7V+ C176.8uF+ C166.8uFIC3LM7812C/TO2201 3IN OUT221D81N4001D71N4001C210.1uF2C220.1uF+ C23100uF211+ C92200uFD61N4001C200.1uF+ C192200uFR28860R2510k, 10-TurnR261.2kISOLATIONBALANCETRIMMERD5BR62- ++C122200uFC110.1uF2 3IN OUT1C130.1uF+C142200uFD97VR27860D107VC180.1uFGNDGNDC100.1uFIC4LM7815C/TO2201 3IN OUTDNG2R241.2kIC5LM7915C/TO220C150.1uFFigure 3.28 Linear regulators generate the various voltages required by the ammeter’s circuitry. In addition, R24–R26 are used to derivean ac signal to balance the measurement circuit during application of 125 V ac to the patient connections.15VAC 1AC BALANCE15VAC 2140
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DESIGN AND DEVELOPMENTOF MEDICAL EL
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Copyright © 2005 by John Wiley & S
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CONTENTSPREFACEDISCLAIMERABOUT THE
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xPREFACEThe book addresses the prac
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DISCLAIMERThe projects in this book
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ABOUT THE AUTHORSDavid Prutchi is V
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2 BIOPOTENTIAL AMPLIFIERSGainG70.7%
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4 BIOPOTENTIAL AMPLIFIERSVolumeCond
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6 BIOPOTENTIAL AMPLIFIERSWarning! T
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8 BIOPOTENTIAL AMPLIFIERSIfRf-VccRi
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10 BIOPOTENTIAL AMPLIFIERSFigure 1.
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12 BIOPOTENTIAL AMPLIFIERSof the sk
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14 BIOPOTENTIAL AMPLIFIERScontamina
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20 BIOPOTENTIAL AMPLIFIERSA way of
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22 BIOPOTENTIAL AMPLIFIERSskin- ele
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26 BIOPOTENTIAL AMPLIFIERSOscillosc
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28 BIOPOTENTIAL AMPLIFIERS+15VV 132
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X1KX100X10JP2Sense3 2 13 2 14 5 6JP
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32 BIOPOTENTIAL AMPLIFIERSgenerator
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36 BIOPOTENTIAL AMPLIFIERSresults i
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38 BIOPOTENTIAL AMPLIFIERSUsing off
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42 BANDPASS SELECTION FOR BIOPOTENT
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5V_ISOIR25.1MR35.1MIR11M2374 8-+65V
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62Figure 2.14 State-variable filter
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64Figure 2.16 Since the cutoff freq
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66Figure 2.17 PSpice simulation res
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OUTOutputOut GND6R42kIC 1UAF42 8Hig
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-OUTOUTGNDININPUTINGND11R5100k1213+
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86Figure 2.35 The slew-rate limiter
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J3OUTPUTBNC2CR81.05KIC 2C406654 3LP
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IC5DCD4093B11CDisplay_InAD131N41484
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OUT+5V_ISOC122uF3284+-IC1A1OPA2130+
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3DESIGN OF SAFE MEDICALDEVICE PROTO
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STANDARDS FOR PROTECTION AGAINST EL
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LEAKAGE CURRENTS 1011. Ground leaka
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Figure 3.2 A universal differential
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DESIGN EXAMPLE: ISOLATED DIFFERENTI
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-15VC6+15VC5.01uFIC2.01uF UA741 -15
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ANALOG SIGNAL ISOLATION USING OPTIC
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LINEAR ANALOG ISOLATION USING OPTOI
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LINEAR ANALOG ISOLATION USING OPTOI
Page 262: NON ISO.POWERSignalOutputJP312ISO.P
Page 266: ISOLATEDPOWERINPUTJ4ISOLATED SIDENO
Page 270: DIGITAL ALTERNATIVE TO SIGNAL ISOLA
Page 274: SOFTWARE FOR THE ISOLATED A/D 121LP
Page 278: POWER SUPPLIES 123Figure 3.17 The n
Page 282: ADDITIONAL PROTECTION 125In additio
Page 286: TESTING FOR COMPLIANCE 127designed
Page 290: TESTING FOR COMPLIANCE 129Voltage-M
Page 294: TESTING FOR COMPLIANCE 131The frequ
Page 298: SelectorSelectorPatientConnectionsP
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Page 306: ISOLATED 125 VACAC BALANCE125VAC TO
Page 310: TABLE 3.3 Normal and Fault Conditio
Page 316: 117VACHOTNEUTRAL12MAIN ACPOWERSW2SW
Page 320: TRIPD61N4148BufferR220k 1.0%Precisi
Page 324: 146 DESIGN OF SAFE MEDICAL DEVICE P
Page 328: 148 ELECTROMAGNETIC COMPATIBILITY A
Page 360: 164Figure 4.11 The intermediate-fre
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166 ELECTROMAGNETIC COMPATIBILITY A
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Metal BoxHot(Black)L150uHC11.0uF 40
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5SIGNAL CONDITIONING, DATA ACQUISIT
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UNIVERSAL SENSOR INTERFACE 207Figur
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Figure 5.3 Schematic diagram of the
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UNIVERSAL SENSOR INTERFACE 211As co
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UNIVERSAL SENSOR INTERFACE 213dat
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UNIVERSAL SENSOR INTERFACE 215TABLE
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UNIVERSAL SENSOR INTERFACE 217For d
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UNIVERSAL SENSOR INTERFACE 219Figur
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UNIVERSAL SENSOR INTERFACE 22111421
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UNIVERSAL SENSOR INTERFACE 223TO J2
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SAMPLING RATE AND THE NYQUIST THEOR
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FREE DATA ACQUISITION CARD IN YOUR
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OUTOUTGNDTOSOUNDCARDR1C110kR21000.1
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FREE DATA ACQUISITION CARD IN YOUR
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SPECTRAL ANALYSIS 233TABLE 5.4 Some
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SPECTRAL ANALYSIS 235In most instan
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w n x n e 2πjf n ∆t X( f ) ∆t
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SPECTRAL ANALYSIS 239High-Resolutio
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SPECTRAL ANALYSIS 241Figure 5.19 Po
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SPECTRAL ANALYSIS 243order, but an
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SPECTRAL ANALYSIS 245Figure 5.21 A
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REFERENCES 247apart over the biceps
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250 SIGNAL SOURCES FOR SIMULATION,
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OUTPUTJ2SMBR10502WJP1JUMPER 3JP2JUM
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T112VAC 1AD11N4005D31N4005+ C45+220
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C791uFR112Z_SIG_OUTZ Amplitude~0-50
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294Figure 6.31 A potentiostat-galva
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7STIMULATION OF EXCITABLE TISSUESAn
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STIMULATION OF EXCITABLE TISSUES 30
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EXTRACELLULAR STIMULATION 309membra
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CLINICAL USES OF ELECTRICAL STIMULA
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9. Control of Parkinsonian tremor.
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TABLE 7.1(Continued)CLINICAL USES O
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DIRECT STIMULATION OF NERVE AND MUS
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ELECTRODE 1ELECTRODE 2I_OUTR3+15V_S
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WAVEFORM:CLOSED = MONOPHASICOPEN =
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BT1 BT2 BT3 BT41.5V1.5V1.5V1.5VSW1P
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ELECTRODE 3BODY PARTTO BESTIMULATED
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• Cardiac demand pacemakers that
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MAGNETIC STIMULATION 347trast, a ma
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SCR1ST330S16P0L1COILEXTREME DANGER!
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MAGNETIC STIMULATION 351• TOFF: t
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MAGNETIC STIMULATION 353+ -d/dtCOIL
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MAGNETIC STIMULATION 355tube cap. A
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OTHER CLINICAL APPLICATIONS OF ELEC
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Hodgkin, A. L., and A. F. Huxley, A
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8CARDIAC PACING AND DEFIBRILLATIONW
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BRADYARRHYTHMIAS 371As a result, on
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THE FIRST PACEMAKERS 373designed in
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Figure 8.4 The output of a PSpice s
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THE FIRST PACEMAKERS 377V SenseA Se
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Pacing Mode This parameter selects
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EXTERNAL VVI PACEMAKER 381EXTERNAL
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Figure 8.11 presents the schematic
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VDDV+AnodeACTI VE_DISCHARGEQ1BSS84R
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EXTERNAL VVI PACEMAKER 387TimeStamp
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EXTERNAL VVI PACEMAKER 389}}default
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SOFTWARE TESTING 391Of course, safe
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IMPEDANCE TECHNIQUE 393contraction)
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IMPEDANCE TECHNIQUE 395
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IMPEDANCE TECHNIQUE 397C110.1uFR205
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DEMOD_OUT+15Viso-15VisoINPUTJ5SMC39
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INTRACARDIAC IMPEDANCE SENSOR 401Le
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INTRACARDIAC IMPEDANCE SENSOR 403At
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INTRACARDIAC IMPEDANCE SENSOR 405Fi
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VENTRICULAR TACHYARRHYTHMIAS 407Tim
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1.61.41.2Output Voltage10.80.60.4DV
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VENTRICULAR TACHYARRHYTHMIAS 411Imp
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DEFIBRILLATION 413stimulus waveform
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SW5Safety InterlockF12AF20.25ASW1Po
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SHOCK BOX PROTOTYPE 417defibrillati
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SHOCK BOX PROTOTYPE 419Figure 8.34
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Figure 8.36 Interconnection diagram
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SHOCK BOX PROTOTYPE 423In operation
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SHOCK BOX PROTOTYPE 425markets and
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Figure 8.40 A H-bridge switch confi
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SHOCK BOX PROTOTYPE 429V_CAP_OUTR56
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SHOCK BOX PROTOTYPE 431onboard the
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SHOCK BOX PROTOTYPE 433+12_VBATC791
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SHOCK BOX PROTOTYPE 435value by the
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CARDIAC FIBRILLATOR 4373. Every 1 s
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CONCLUDING REMARKS 439+9VS1R1IC15CO
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EPILOGUEOut of clutter, find simpli
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PATH THROUGH THE FDA 443intended us
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the industry is undergoing profound
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APPENDIX ASOURCES FOR MATERIALS AND
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SOURCES FOR MATERIALS AND COMPONENT
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APPENDIX BFTP SITE CONTENTftp://ftp
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FTP SITE CONTENT 453• LPT8FAST.BA
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FTP SITE CONTENT 455Folder: Redistr
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458 INDEXCentro de Construccion de
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460 INDEXPacemaker(s) (Continued)pu
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