Literature Review: Pregnant and breastfeeding ... - Eat For Health

maternal atopyInhalant sensitisation (positive skin prick test for a range of allergens)n/N OR (95%) aOR (95% CI) p-value for trendAllergic mothers≤ 1 serve/month 27/62 (43.5%) 1 1 0.761 serve/week 63/138 (50.7%) 1.33 (0.73 to 2.43) 0.89 (0.30 to 2.60)≥2-3 serves/week 48/83 (42.2%) 0.94 (0.48 to 1.83) 0.74 (0.23 to 2.37)*adjusted for age, number of older siblings, allergy clinics, maternal age, gestation age, gender, maternal education, paternal atopy,maternal atopyNon-allergic mothers≤ 1 serve/month 69/136 (50.7%) 1 1 0.621 serve/week 137/330 (41.5%) 0.68 (0.46 to 1.02) 0.70 (0.38 to 1.30)≥2-3 serves/week 92/197 (46.7%) 0.85 (0.54 to 1.31) 0.55 (0.28 to 1.08)*adjusted for age, gender, number of older siblings, allergy clinics, maternal age, number of pregnancies, maternal occupation, paternalatopy, asthma, oculorhinitisInhalant sensitisation in whole population:≥2-3 serves/week: aOR* 0.57 95% CI 0.32 to 1.03*adjusted for age, gender, oculorhinitis, asthma, number of older siblings, allergy clinics, maternal age, number of pregnancies, maternaleducation, preterm labour, paternal atopy, maternal atopy: did not vary significantly with amount of butter intakeFollowupNAConfoundingAnalyses only adjusted for a limited number of factors; different factors were used for the analyses of allergic and non-allergic mothers; and for food andinhalant sensitisations (included if significant in univariate analyses).Risk of bias Moderate risk of bias: recall bias likely for women remembering diet during a pregnancy up to 17 years earlier; data for maternal atopy available for 988of the 1044 consecutively recruited children (94.6%); data for maternal fish intake during pregnancy available for 946/988 (95.7%); children attendingallergy clinics likely to be different for a general population of children.RelevanceDiets of pregnant Italian women may differ from those of Australian women e.g. there were low levels of maternal margarine and butter consumption inthis studyOther comments Clinical significance of skin prick tests?Wide age range (1 to 18?) makes interpretation of allergic sensitisations difficultDietary guidelines for pregnant and breastfeeding women: evidence report268