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Literature Review: Pregnant and breastfeeding ... - Eat For Health

Literature Review: Pregnant and breastfeeding ... - Eat For Health

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Reference Olafsdottir 2006Dietary patterns <strong>Eat</strong>ing more (in either early or late pregnancy)Study typeProspective cohort studyLevel of evidence II (aetiology)SettingIcel<strong>and</strong>FundingIcel<strong>and</strong>ic Research Council, University of Icel<strong>and</strong> Research FundParticipants495 r<strong>and</strong>omly selected healthy pregnant women attending a routine first antenatal visitBaseline comparisons See confounding belowDietary assessment FFQTimingAt 11-15 weeks gestation; <strong>and</strong> 34-37 weeks gestation (to reflect food intake for the last 3 months)Comparison<strong>Eat</strong>ing more versus not eating more than usual (in either early or late pregnancy)OutcomesGestational weight gain (optimal weight gain defined as 12.1 to 18.0 kg for women with normal pre-pregnancy weight; <strong>and</strong> 7.1 to 12.0 kg for overweightwomen)Results20% of the 301 women with BMI < 25 at first visit had excessive gestational weight gain;55% of the 194 women with BMI ≥ 25 at first visit had excessive gestational weight gain<strong>Eat</strong>ing more in early pregnancyAt least optimal weight gain: aOR 1.00 95% 0.55 to 1.84Excessive weight gain: aOR 1.60 95% CI 0.91 to 2.79<strong>Eat</strong>ing more in late pregnancyAt least optimal weight gain: aOR 3.32 95% 1.81 to 6.09Excessive weight gain: aOR 2.04 95% CI 1.17 to 3.58FollowupConfoundingRisk of biasRelevanceOther commentsTo birthAdjusted for maternal age, gestational length <strong>and</strong> smokingLow to moderate risk of bias: of the 549 women enrolled, 495 (90%) completed the study; 54 women were excluded (17 miscarriage/stillbirths, 5 sets oftwins or triplets, 17 preterm births, 15 missing data); 89 women did not complete FFQ at the second timepoint <strong>and</strong> so only 406 women could beincluded for measures relating to late pregnancy; limited number of confounders used in adjusted analysesLikely to be reasonably relevant to Australian womenPregnancy <strong>and</strong> Breastfeeding Dietary Patterns49

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