Literature Review: Pregnant and breastfeeding ... - Eat For Health

Reference Duarte-Salles 2010Dietary patterns Diet high in polycyclic aromatic hydrocarbons (PAH) – from high consumption of shellfish, processed/cured meats, milk/yoghurt, bread, sweet dairyfoods, alcoholic beverages and sugar and benzo(a)pyrene (BaP) – from processed or cured meat, nuts and fats and oilsStudy typeProspective cohort studyLevel of evidence II (aetiology)SettingSabadell, SpainFundingSpanish Ministry of Health, Instituto de Salud Carlos III, Generalitat de Catalunya-CIRITParticipants 657 women recruited in the first trimester of pregnancy (part of INMA project) from July 2004 to July 2006Baseline comparisons Not reportedDietary assessment FFQTiming“during first and third trimesters”ComparisonAmounts of dietary PAH and total PAH; and BaPOutcomesBirthweightResultsBirthweightBaP in first trimester significantly associated with lower birth weight (after adjusting for potential confounders such as cigarette smokeexposure): mean birthweight 142.73 lower for the fourth compared with the first quartile of dietary BaP (p < 0.05);BaP in third trimester not significantly associated with birthweight;Total PAH in either first or third trimesters not associated with birthweightFollowupConfoundingRisk of biasRelevanceOther commentsTo birthNot reported which confounders were used in analyses (except for cigarette smoke exposure)Unclear risk of bias: confounders and birthweight results not fully reportedWomen in this study likely to consume more cured meats than Australian womenSmoking during pregnancy was associated with higher dietary PAH in the study populationPregnancy and Breastfeeding Dietary Patterns29