SOYBEAN AND HEALTH - University of Macau Library

Soybean Oil: Production Process, Benefits and Uses in Pharmaceutical Dosage Form 307if blended with high stability oil like cottonseed or palm oil. Having a high value of Omega-3, Omega-6 and Vitamin E and low value of price makes soybean oil an vital nutriment fordaily consume.Both cold pressing and refining of soybean oil are commonly used and beneficial processingsystems. In cold pressing while high temperature have not been used, the deodorizationstep of refining needs high temperature and pressure to eliminate of impurities comes fromextracted raw material. Refining has more steps than cold pressing, like, degumming,neutralization, bleaching, winterizing and deodorizing. Moreover conditions of crude oilreceiving and unloading, storage, refined oil storage and loading steps effects the qualityand hygiene of last product.Soybean oil has been used in the pharmaceutical formulations. In conclusion, soybean oil isnot only used in food products but is also used as pharmaceutical excipients to produce anovel, biocompatible formulations which are cost effective, non-irritating, and capable ofbeing sterilized before application.Test JP 2001 PhEur 2005 USP 28Identification - + -Characters - + -Specific gravity 0.916–0.922 0.922 0.916–0.922Refractive index - 1.475 1.465–1.475Heavy metals - - 0.001%Free fatty acids - - +Fatty acidcomposition- + +Acid value 0.2 0.5 -Iodine value 126–140 - 120–141Saponificationvalue188–195 - 180–200Unsaponifiablematter1.0% 1.5% 1.0%Cottonseed oil - - +Peroxide - 10.0 or 5.0 (a) +Alkalineimpurities- + -Brassicasterol - 0.3% -Water - 0.1% (a) -(a)In soybean oil intended for parenteral use.Table 1. Pharmacopeial specifications for soybean oil4. AcknowledgmentThe authors would like to thank the management of ZADE Edible Oil Refinery & Cold PressedOil Plant for assisting on the preparation of this review.