5 The role of quorum-sensing in the virulence of Pseudomonas ...

Strain Mouse Timepoint HB CI GC Score
LES400 1 18hr � Heavy Medium 3
2 18hr � Heavy Medium 3
1 52hr � Medium Heavy 4
2 52hr � Medium Heavy 4
1 96hr � Heavy Medium 3
2 96hr � Medium Medium 3
LES431 1 96hr � Heavy Heavy 5
2 96hr � Heavy Medium 4
LESB58 1 18hr � Heavy Heavy 4
2 18hr � Heavy Heavy 4
1 52hr � Heavy Heavy 4
2 52hr � Heavy Heavy 4
1 96hr � Medium Low 3
2 96hr � Medium Low 3
LESB65 1 18hr � Heavy Medium 4
2 18hr � Heavy Medium 4
1 55hr � Heavy Heavy 4
2 55hr � Heavy Heavy 5
1 96hr � Heavy Heavy 4
2 96hr � Heavy Heavy 5
Table 5-8 shows the histopathology scores for lungs recovered at 18, 52 (55) and 96 hours post-
infection with 2x10 6 CFU/50µl; n=2 for each strain
Key: HB = hypertrophy of bronchi, CI = cellular infiltration and GC = general consolidation of
lung parenchyma
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