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Carbohydrates and Health

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Methodology<br />

S.4 Only evidence from prospective cohort studies <strong>and</strong> r<strong>and</strong>omised controlled trials<br />

was considered for this report. SACN commissioned systematic reviews of the<br />

evidence on cardio-metabolic, colo-rectal <strong>and</strong> oral health in literature published<br />

from 1990 up to <strong>and</strong> including December 2009, November 2010 <strong>and</strong> January 2011<br />

respectively. In order to ensure that the evidence base was as current as possible<br />

while SACN was undertaking this review, the literature searches were subsequently<br />

updated for studies on important health outcomes published up to June 2012. The<br />

evidence was assessed using the SACN Framework for the Evaluation of Evidence<br />

<strong>and</strong> graded according to a system devised specifically for this review.<br />

S.5 SACN has evaluated evidence assessing whether intakes of specific carbohydrates<br />

are a factor in the risk for cardiovascular disease, obesity, type 2 diabetes mellitus<br />

<strong>and</strong> colo-rectal cancers. The relationship between dietary carbohydrate intake<br />

<strong>and</strong> a large number of risk factors <strong>and</strong> markers related to these diseases has been<br />

considered. Evidence on the relationship of carbohydrates to oral health has also<br />

been discussed. For many of the risk factors <strong>and</strong> disease markers identified, there<br />

was insufficient evidence of the required quality, therefore SACN has based its<br />

recommendations on those conclusions where the committee considered the<br />

evidence base to be of sufficient st<strong>and</strong>ard according to the SACN Framework for<br />

the Evaluation of Evidence <strong>and</strong> the grading system developed for this review.<br />

S.6 In this report, evidence has been considered under the broad headings of total<br />

carbohydrates; sugars <strong>and</strong> sugars-sweetened foods <strong>and</strong> beverages; starch <strong>and</strong><br />

starch-rich foods; dietary fibre; non-digestible oligosaccharides, resistant starch,<br />

polyols <strong>and</strong> polydextrose; <strong>and</strong> the glycaemic characteristics of carbohydrate-rich<br />

foods <strong>and</strong> diets (glycaemic index <strong>and</strong> glycaemic load). The individual chapters<br />

provide extensive detail on the evidence considered for each type of carbohydrate<br />

in relation to health outcomes, SACN’s view of the strength of the evidence <strong>and</strong><br />

its conclusions.<br />

Conclusions <strong>and</strong> recommendations<br />

S.7 The main findings of this review of the evidence on carbohydrates <strong>and</strong> health,<br />

upon which SACN has based its recommendations, are set out below. The report<br />

provides a detailed consideration of all the evidence considered by SACN.<br />

Total dietary carbohydrate<br />

S.8 Overall, the evidence from both prospective cohort studies <strong>and</strong> r<strong>and</strong>omised<br />

controlled trials indicates that total carbohydrate intake appears to be neither<br />

detrimental nor beneficial to cardio-metabolic health, colo-rectal health <strong>and</strong><br />

oral health. However, this report highlights that there are specific components<br />

or sources of carbohydrates which are associated with other beneficial or<br />

detrimental health effects. The hypothesis that diets higher in total carbohydrate<br />

cause weight gain is not supported by the evidence from r<strong>and</strong>omised controlled<br />

trials considered in this review.<br />

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