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Carbohydrates and Health

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Table A4.3: Soft drink <strong>and</strong> fruit juice trial design<br />

Study Trial design Country Fluoride Age (y) Subject<br />

characteristics<br />

Dental erosion<br />

method <strong>and</strong><br />

exposure time<br />

Rugg-Gunn et<br />

al., 1998<br />

XO – no<br />

washout<br />

Engl<strong>and</strong> NR NR 11 adults Bovine<br />

permanent<br />

incisor enamel<br />

mouth palatal<br />

appliances<br />

analysed by<br />

profilometer<br />

<strong>and</strong> scanning<br />

electron<br />

microscopy<br />

West et al.,<br />

1998<br />

XO – 1 wk<br />

washout<br />

Engl<strong>and</strong> No tooth<br />

brushing<br />

allowed when<br />

appliance in<br />

situ<br />

mean 24,<br />

range 20-30<br />

10 adults Human third<br />

molar teeth<br />

enamel<br />

in palatal<br />

appliances<br />

analysed by<br />

profilometer<br />

<strong>and</strong> surface<br />

microhardness<br />

Hughes et al.,<br />

1999a<br />

XO – 2 ½<br />

d washout<br />

Engl<strong>and</strong> No tooth<br />

brushing<br />

allowed when<br />

appliance in<br />

situ<br />

mean 28,<br />

range 20-34<br />

12 adults Human third<br />

molar teeth<br />

enamel<br />

in palatal<br />

appliances<br />

analysed by<br />

profilometer<br />

NR, not reported; y, year; d, day; XO, cross-over.<br />

Duration (d) Dietary<br />

assessment<br />

method<br />

Basal diet Intervention Control<br />

intervention<br />

7 NR No<br />

restrictions<br />

– volunteers<br />

asked to<br />

maintain<br />

similar eating<br />

<strong>and</strong> drinking<br />

patterns<br />

during<br />

experimental<br />

periods<br />

Dental blocks<br />

dipped with<br />

either noncalorically<br />

sweetened<br />

phosphoric<br />

acid-based<br />

cola drink or<br />

non-calorically<br />

sweetened<br />

citric acid-based<br />

orange drink<br />

for 15 minutes 4<br />

times/d<br />

Dental blocks<br />

dipped with<br />

distilled<br />

water 4<br />

times/d<br />

15 Compliance<br />

questionnaire<br />

completed<br />

each study<br />

day<br />

Only tea,<br />

coffee or<br />

water could<br />

be consumed<br />

while the<br />

appliances<br />

were in situ<br />

250ml orange<br />

juice 4 times/d<br />

250ml<br />

mineral water<br />

4 times/d<br />

15 Compliance<br />

questionnaire<br />

completed<br />

each study<br />

day<br />

Only tea,<br />

coffee or<br />

water could<br />

be consumed<br />

while the<br />

appliances<br />

were in situ<br />

250ml orange<br />

juice 4 times/d<br />

250ml<br />

mineral water<br />

4 times/d<br />

Funding source<br />

Proctor <strong>and</strong><br />

Gamble Ltd.<br />

Smith-Kline<br />

Beecham<br />

Consumer<br />

<strong>Health</strong>care<br />

Smith-Kline<br />

Beecham<br />

Consumer<br />

<strong>Health</strong>care<br />

218

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