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Carbohydrates and Health

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ackgrounds or from lower social status groups being substantially more likely to<br />

have decay in most age groups, with the differences being most clear cut among<br />

younger children (Public <strong>Health</strong> Engl<strong>and</strong>, 2013). Extraction of carious teeth is the<br />

most common cause for hospital admission for young children in the UK (Elmer<br />

et al., 2014).<br />

Markers <strong>and</strong> measures <strong>and</strong> their related health outcomes<br />

Table 4.1: Risk factors <strong>and</strong> measures for cardio-metabolic <strong>and</strong> colo-rectal health<br />

Risk factors <strong>and</strong> measures considered<br />

Blood pressure:<br />

Blood pressure<br />

Systolic blood pressure<br />

Diastolic blood pressure<br />

Fasting blood lipid concentrations:<br />

Total cholesterol<br />

HDL-cholesterol<br />

LDL-cholesterol<br />

LDL-cholesterol: HDL-cholesterol<br />

Total cholesterol: HDL-cholesterol<br />

Non-HDL-cholesterol<br />

Triacylglycerol<br />

Non esterified fatty acids<br />

Apolipoproteins (A1 & B)<br />

Lipoprotein (a)<br />

Coronary & vascular factors:<br />

Coronary calcification<br />

Aortic calcification<br />

Carotid plaque formation<br />

Pulse wave velocity<br />

Flow mediated dilatation<br />

Vascular compliance<br />

Arterial compliance<br />

Inflammatory markers:<br />

Acute phase protein (including CRP, serum<br />

amyloid A)<br />

Cytokines (including IL-6, tumour necrosis<br />

factor-α)<br />

Adhesion molecules<br />

Clotting cascade (including clotting<br />

associated factor PAI-1, fibrinogen, factor VII)<br />

Related<br />

outcomes<br />

cardiovascular<br />

diseases <strong>and</strong><br />

renal impairment<br />

cardiovascular<br />

diseases<br />

cardiovascular<br />

diseases<br />

cardiovascular<br />

diseases <strong>and</strong><br />

type 2 diabetes<br />

mellitus<br />

References<br />

MacMahon et al.,<br />

1990; Whelton,<br />

1994; Lewington<br />

et al., 2002; Bidani<br />

& Griffin, 2002;<br />

Shammas, 2007<br />

Gordon & Rifkind,<br />

1989; Rader et al.,<br />

2003; Lewington et<br />

al., 2007; Shammas,<br />

2007; Brainin<br />

& Heiss, 2009;<br />

Goldberg et al., 2011;<br />

Miller et al., 2011<br />

Wilson et al., 2001;<br />

Kelm, 2002; Witte et<br />

al., 2005; Mattace-<br />

Raso et al., 2006;<br />

Yeboah et al., 2007;<br />

Finn et al., 2010;<br />

Janner et al., 2012<br />

Ross, 1999; Libby<br />

et al., 2002; Kolb &<br />

M<strong>and</strong>rup-Poulsen,<br />

2005; Basu et al.,<br />

2006; Wang et al.,<br />

2013<br />

34

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