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Abstract title
Q-t dispersion in Diabetic patients with and without obesity
Dr. Hassan Shehata
Mervat M attia, ahmmed M boghdady, eman a sabet, usama a arafa, ali taha hassan, adel a elsayed,
hassan a hassanein.
ABSTRACT: Corrected Qt interval (Qtc) and Qt dispersion (Qtd) prolongation, whatever the cause,
is proarrhythmic, and this alone contributes to an increased probability of arrhythmic sudden
cardiac death( sCD).
the risk of fatal arrhythmias in diabetic and obese people especially those with morbid obesity is
thought to be correlated with a prolonged electrocardiographic Qt interval and increased (Qtd) .
this study aimed to evaluate the Qtd in diabetic patients and its correlation with obesity as a corisk
factor for cardiovascular mortality and sudden cardiac death. two groups are included in the
study ;-(Group 1);control group, (Group 2); 100 diabetic patients ,50 of them were obese (Group
2a) and 50 were non obese (Group 2b) , their age ranged from 20-61 years ( mean 42.83 ± 15.18
years), 55 males (44.82 %) and 61 females(55.18 %).the study revealed a significant increase in Qt
interval , (Qtc) and Qtd in diabetic patients when compared to control individuals , and this increase
had greater significance in obese diabetic patients compared to non obese diabetic patients with
evident link not only to bMi but also to waist circumference(WC) and waist/hip ratio(Whr). in this
study , the risk of prolonged Qtc and increased Qtd in diabetic patients was higher in those with
worse glycaemic and dyslipidaemic control, but increase in Qtd was independent of age and sex
as a cardiovascular risk factors.
in addition , the study revealed more increase in Qtc and Qtd in diabetic patients with autonomic
neuropathy than those without autonomic
neuropathy. from this point of view, this study have clinical implications, further supporting the
need to obtain both good glycemic and lipidemic control as well as to perform physical activity and
keep weight in the normal range in diabetic patents.
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