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Abstract Title
Study of Silent Myocardial Ischemia In Type 2 Diabetic Males
Ali Kassem
Yehia T Kishk**, Ali M. Kassem*, Ali T Hassan* Adel A El-Sayed, M.Abdel Wahab*
*faculty of Medicine, sohag university, ** faculty of Medicine, assiut university
introduction: accelerated coronary and peripheral vascular atherosclerosis is one of the most
common and chronic complications of diabetes mellitus. a recent aspect of coronary artery disease
in this condition is its silent nature.
aim of the work: is to detect the prevalence of silent myocardial ischemia (sMi) in type 2 diabetic
males in our locality and to select male diabetic population who should be screened for sMi.
patients and methods: the study was carried out on 100 type 2 diabetic males with negative
history of angina and 30 healthy males. Laboratory estimation of f bG level, lipid profile , (hba1c),
microalbuminurea, and C-reactive protein were done for all participants. non invasive tests (nits)
including 12 leads resting eCG, trans-thoracic echocardiography, treadmill exercise eCG, myocardial
perfusion imaging were done for all participants and patients positive for one or more nits were
subjected for coronary angiography.
results: (29%) were positive for one or more nits in the patients group Vs (3.3%) in the control.
after coronary angiography, 20 patients were positive for significant coronary artery stenosis.
there were statistical significant difference between the two groups as regard family history of DM
and ihD, hypertension, and obesity with higher levels of microalbuminurea, C-reactive protein,
total cholesterol, and triglycerides in the patients group Vs control.
Conclusion: type 2 diabetic male patients should be screened for detection of sMi when age above
50, diabetes duration is more than 5 years , presence of two or more cardiac risk factors and/or
patients suffering from one or more of the chronic diabetic complications.
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