Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
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Asymptomatic/Subcl<strong>in</strong>ical AMR: Increased risk of<br />
Cardiac Allograft Vasculopathy (CAV)<br />
43 with AMR<br />
21<br />
asymptomatic<br />
and untreated<br />
(AsAMR)<br />
1997 - 2001<br />
246 transplants<br />
86 controls<br />
matched for age,<br />
sex, time from tx<br />
22<br />
symptomatic<br />
(EF ≤ 40%)<br />
(TxAMR)<br />
9<br />
hemodynamic<br />
compromise<br />
Endothelial cell <strong>in</strong>jury!<br />
Wu et al, J <strong>Heart</strong> and Lung Transplant 2009; 28:417-22
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