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Antibody Mediated Rejection in Heart Transplantation

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Assess<strong>in</strong>g Panel Reactive Antibodies:<br />

Screen<strong>in</strong>g for the Presence of Antibodies<br />

• Screen<strong>in</strong>g<br />

– Low Risk: PRA < 10%<br />

– Moderate Risk:<br />

PRA 10-25%<br />

– High Risk: PRA > 25%<br />

• Specification<br />

– Identification of<br />

anti-HLA Ab<br />

• Quantification<br />

– Are they cytotoxic?<br />

Survival %<br />

Nwakanma LU Annals Thoracic Surg 2007 84:1556-1563

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