17.12.2012 Views

Antibody Mediated Rejection in Heart Transplantation

Antibody Mediated Rejection in Heart Transplantation

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Challenges of<br />

<strong>Antibody</strong>-<strong>Mediated</strong> <strong>Rejection</strong><br />

• Diagnosis<br />

– Are symptoms required? No<br />

– Cl<strong>in</strong>ical versus pathological? Pathological<br />

• Prevention<br />

– How do we identify patients at high risk for<br />

AMR?<br />

– Can high-risk patients be treated prior to<br />

transplant?<br />

• Treatment<br />

– How should AMR be treated?<br />

– If the <strong>in</strong>itial therapy fails, what next?

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