Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
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What matters cl<strong>in</strong>ically:<br />
The Calculated PRA<br />
• How easy will it be to f<strong>in</strong>d<br />
a donor for my patient<br />
await<strong>in</strong>g transplant?<br />
• cPRA def<strong>in</strong>es the<br />
frequency of the<br />
unacceptable HLA <strong>in</strong> the<br />
donor population<br />
• Step 3: Assess cPRA<br />
– cPRA 10% = 90% of<br />
donors would be a<br />
match<br />
– cPRA 80% = only 20%<br />
of donors would be a<br />
match<br />
cPRA 53% = only 47%<br />
donors would be a match<br />
http://optn.transplant.hrsa.gov/resources/professionalResources.asp?<strong>in</strong>dex=78
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