Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
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Assess<strong>in</strong>g Panel Reactive Antibodies:<br />
Identification by Fluorescent Bead Assays<br />
• Screen<strong>in</strong>g<br />
– Low = PRA < 10%<br />
– Moderate = PRA<br />
10-25%<br />
– High = PRA > 25%<br />
• Specification<br />
– Identification of<br />
anti-HLA Ab<br />
• Quantification<br />
– Are they cytotoxic?<br />
Laser<br />
Freq<br />
Fluorescence
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