Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
Antibody Mediated Rejection in Heart Transplantation
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Acute therapy<br />
determ<strong>in</strong>ed by<br />
cl<strong>in</strong>ical picture<br />
Normal EF/hemos,<br />
no DSA, no rejection<br />
EMBx/echos per<br />
protocol<br />
PRA q 6m<br />
After the dust settles. . .<br />
AMR Ma<strong>in</strong>tenance Protocol<br />
MMF à� PSI<br />
Repeat echo, EMBx,<br />
PRAs 1-2w post rx<br />
Photopheresis<br />
Persistent low EF,<br />
abnormal hemos, or DSA<br />
?<br />
IV Ig, rituximab,<br />
bortezomib