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Antibody Mediated Rejection in Heart Transplantation

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Asymptomatic AMR: Lessons Learned<br />

• Asymptomatic AMR if untreated:<br />

– Increased <strong>in</strong>cidence of CAV compared to patients<br />

with no AMR and patients with treated,<br />

symptomatic AMR<br />

– Increased mortality compared to patients with<br />

treated cellular or mixed rejection<br />

• Conclusion<br />

– The diagnosis of AMR should be pathological, not<br />

cl<strong>in</strong>ical<br />

– Asymptomatic AMR should be treated

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