ToxCast and Tox21: High Throughput Screening for Hazard & Risk ...
ToxCast and Tox21: High Throughput Screening for Hazard & Risk ...
ToxCast and Tox21: High Throughput Screening for Hazard & Risk ...
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96-well plate<br />
<strong>Tox21</strong> <strong>Screening</strong> g <strong>Throughput</strong> g p<br />
� 8 rows x 12 columns<br />
� 88 test samples<br />
384-well plate<br />
4 x 96-well plates<br />
If @ 100 microtiter plates per day:<br />
samples Time to screen<br />
1 MM samples<br />
§ Plate <strong>for</strong>mat samples /day Time to screen<br />
(wells/day) 1 MM samples<br />
§ Plate <strong>for</strong>mat<br />
/day<br />
(wells/day)<br />
96-well<br />
384-well<br />
1,536-well<br />
8,800 (9,600)<br />
35,200 (38,400)<br />
Office of Research <strong>and</strong> Development<br />
Computational Toxicology Research Program<br />
140,800 (153,600)<br />
4 months<br />
4 weeks<br />
7 days<br />
� 16 rows x 32 columns<br />
� 352 test samples<br />
1536-well plate<br />
16 x 96-well plates<br />
� 32 rows x 48 columns<br />
� 1,408 test samples<br />
§ wells remaining after subtraction of control wells;<br />
NCGC uses left 4 columns of a 1536-well plate <strong>for</strong><br />
control wells<br />
9