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ToxCast and Tox21: High Throughput Screening for Hazard & Risk ...

ToxCast and Tox21: High Throughput Screening for Hazard & Risk ...

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<strong>ToxCast</strong> <strong>and</strong> <strong>Tox21</strong> <strong>High</strong> <strong>Throughput</strong> <strong>Screening</strong><br />

of Chemical Bioactivity<br />

• Addresses chemical screening <strong>and</strong> prioritization<br />

needs <strong>for</strong> chemicals regulated by EPA<br />

• Comprehensive use of HTS technologies to<br />

generate biological fingerprints <strong>and</strong> predictive<br />

signatures<br />

• Committed to stakeholder involvement <strong>and</strong><br />

transparency p y<br />

• Communities of Practice- Chemical Prioritization;<br />

Exposure<br />

• Release of all data upon peer review publication<br />

Office of Research <strong>and</strong> Development<br />

Computational Toxicology Research Program<br />

7

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