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Molecular Characterization and Gene Expression Profiling ... - CUSAT

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Chapter 2<br />

in the shrimp body, by the presence of haemocytes, could combine<br />

antimicrobial <strong>and</strong> chitin-binding properties that may be important in<br />

interactions between immune function <strong>and</strong> developmental function through<br />

the synthesis of exoskeleton in shrimp. These possible multifunctional<br />

properties of antimicrobial peptides represent an important new area to be<br />

investigated. The study of such AMP functions <strong>and</strong> expression in shrimp is<br />

particularly important for fundamental underst<strong>and</strong>ing of shrimp immunity<br />

<strong>and</strong> for further establishment of disease control in shrimp aquaculture<br />

(Bachere, 2003). Any progress in this field would contribute to a better<br />

underst<strong>and</strong>ing of the penaeid shrimp physiology <strong>and</strong> of their capacity to<br />

respond to pathological injuries (Bachere et al., 2000b). Moreover, from their<br />

unusual features both at the structural level <strong>and</strong> in terms of biological<br />

activity, penaeidins could represent, along with other AMPs, a new<br />

generation of therapeutic agents <strong>and</strong> find potential applications in<br />

aquaculture.<br />

The recent discovery of AMPs in crustaceans provides new clues for<br />

fundamental underst<strong>and</strong>ing of crustacean immunity. The study of such AMP<br />

functions <strong>and</strong> expression in shrimp is particularly important for fundamental<br />

underst<strong>and</strong>ing of shrimp immunity <strong>and</strong> for further establishment of disease<br />

control in shrimp aquaculture (Bachere, 2003). Moreover, from their unusual<br />

features both at the structural level <strong>and</strong> in terms of biological activity, AMPs<br />

represent a new generation of therapeutic agents <strong>and</strong> find potential<br />

applications in aquaculture. Moreover, AMP represents a new generation of<br />

therapeutic agents with potential applications in aquaculture.<br />

<strong>Molecular</strong> <strong>Characterization</strong> <strong>and</strong> <strong>Gene</strong> <strong>Expression</strong> <strong>Profiling</strong> of Antimicrobial Peptides in Penaeid Shrimps<br />

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