Electronic Posters: Neuroimaging - ismrm
Electronic Posters: Neuroimaging - ismrm
Electronic Posters: Neuroimaging - ismrm
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15:30 4441. Anatomical Imaging at 7 T Using 2D GRASE – a Comparison with 2D TSE<br />
Robert Trampel 1 , Robin Martin Heidemann 1 , Robert Turner 1<br />
1 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany<br />
Specific absorption rate (SAR) is a serious problem at high field strengths, especially for sequences such as Turbo Spin-Echo (TSE).<br />
For a given desired tissue contrast, SAR reduction can provide either faster imaging or greater spatial coverage per unit time. By<br />
omitting most of the refocusing pulses of TSE, and replacing them with segmented EPI readouts, GRASE (Gradient-and-Spin-Echo)<br />
incurs much less SAR. Careful comparison of TSE and GRASE images at 7 T showed very similar SNR and contrast. The very slight<br />
decrease in GRASE image quality is balanced by a significant reduction in scan time (x 1/3) or increase in spatial coverage (x 3) as<br />
compared with TSE.<br />
Tuesday 13:30-15:30 Computer 84<br />
13:30 4442. MEG-Guided Surface Coil Imaging at 3 Tesla in Patients with Refractory Epilepsy:<br />
Preliminary Results<br />
Samuel Lapere 1 , Evelien Carrette 2 , Paul Boon 2 , Kristl Vonck 2 , Xavier De Tiège 3 , Eric<br />
Achten 1 , Karel Deblaere 1<br />
1 Department of Radiology, Ghent University Hospital, Ghent, Belgium; 2 Reference Center for Refractory<br />
Epilepsy, Department of Neurology, Ghent University Hospital; 3 Laboratoire de Cartographie Fonctionelle du<br />
Cerveau, ULB Erasmus Hospital Brussels, Belgium<br />
Patients with refractory epilepsy in whom the epileptogenic zone cannot be precisely identified are not likely to undergo resective<br />
surgery. This study aims to assess the potential of surface coil imaging at 3T guided by magnetoencephalography (MEG) to locate the<br />
epileptogenic zone. Fifteen patients with dipole clustering on MEG (indicating the possible epileptogenic zone) were scanned with a<br />
surface coil at 3T. MEG-guided surface coil imaging at 3T showed an added value in the detection of lesions previously not visible or<br />
missed on 3T MRI, and demonstrated an improved delineation and electrophysiological validation of previously known lesions.<br />
14:00 4443. Increased Gray Matter Volume and Cortical Surface Area of Left Pars Opercularis<br />
in Male Orchestral Musicians Correlated Positively with Years of Musical Performance<br />
Ihssan Abdul-Kareem 1 , Andrej Stancak 2 , Laura Parkes 3 , Vanessa Sluming 1<br />
1 School of Health Sciences, Magnetic Resonance and Image Analysis Research Centre, University of Liverpool,<br />
Liverpool, United Kingdom; 2 Department of Psychology, University of Liverpool, Liverpool, United Kingdom;<br />
3 Department of Imaging Science and Biomedical Engineering, School of Cancer and Imaging Sciences,<br />
University of Manchester, Manchester, United Kingdom<br />
Musicians’ brains have long been studied for possible structural brain differences in response to skill acquisition. Broca’s region is<br />
crucial for several musically relevant abilities. We compare manual gray and white matter volume measurements and automatic<br />
cortical surface area measurements of Broca’s region subparts: pars opercularis (POP) and pars triangularis between 26 musicians and<br />
26 non-musicians, all right handed. Musicians have significantly increased gray matter volume and cortical surface area of left POP<br />
which was positively correlated with years of musical performance. We hypothesize that prolonged skill acquisition is an<br />
environmentally enriching activity resulting in structural reorganization of left POP.<br />
14:30 4444. High Resolution Magnetization Transfer Imaging at 3T VS. 1.5T<br />
Ying Wu 1,2 , Christine O'Brien 3 , Christopher Glielmi 4 , Hongyan Du 5 , Robert Edelman 2,3 ,<br />
Ann Ragin 6<br />
1 Radiology , NorthShore University HealthSystem, Evanston, IL, United States; 2 Radiology , University of<br />
Chicago; 3 Radiology, NorthShore University HealthSystem, Evanston, IL, United States; 4 Cardiovascular MR<br />
R&D, Siemens Healthcare; 5 NorthShore University HealthSystem Research Institute; 6 Radiology, Northwestern<br />
University<br />
The increased field strength at 3T significantly improved image quality of high resolution Magnetization Transfer Images, while the<br />
increased scan variation at higher field strength is a potential concern; this investigation indicated that relative to 1.5T, the 3T scanner<br />
is conducive to more consistent MTR measurement over time. Importantly, our findings in the human study indicate excellent<br />
reproducibility in regions such as the hippocampus that are critical regions for detecting early changes in Alzheimer’s disease and<br />
other neurological disorders. Our results demonstrate the promising potential of high resolution MT for clinical application.<br />
15:00 4445. Complex Histogram Based Analysis for Visualization of MRI Data<br />
Peter Arjan Wassenaar 1 , Michael V. Knopp 1 , Petra Schmalbrock 1<br />
1 Radiology, The Ohio State University, Columbus, OH, United States<br />
Especially at high fields, MRI data contain useful information stemming from the presence of paramagnetic material. This work<br />
introduces a new approach to visualizing complex MRI data based on the concept of complex histograms. Complex histograms<br />
provide a representation of both magnitude and phase data simultaneously. Furthermore, a complex color mapping scheme is<br />
introduced for the visualization of complex images, while retaining both magnitude and phase information. Finally, complex<br />
histograms may provide the starting point to tissue segmentation through constraints defined in the complex plane.