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Conférences Servier - GRSNC - Université de Montréal

Conférences Servier - GRSNC - Université de Montréal

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CASTELLUCCI, VincentTél. bureau: (514) 346-1111 ex t. 4353Physiologie(514) 343-4583 Université <strong>de</strong> MontréalC.P. 6128, Succ. Centre-ville, Montréal (Québec)Fax: (514) 343-5751 Canada H3C 3J7URL site WWW:E-Mail: vincent.castellucci@umontreal.ca URL personnel CV:CASTELLUCCI, VincentStatut universitaire / University statusProfesseur titulairePhysiologieFaculté <strong>de</strong> mé<strong>de</strong>cineUniversité <strong>de</strong> MontréalAppartenance à d'autres groupes / Affiliation with other groupsVice-doyen adjoint à la recherche, Faculté <strong>de</strong> mé<strong>de</strong>cine, Université <strong>de</strong> MontréalMembre du Centre <strong>de</strong> recherche en sciences neurologiques (CRSN)Directeur, Groupe d'IRSC sur la transmission synaptique et la plasticitéMembre du Groupe <strong>de</strong> recherche FRSQ sur le système nerveux central (<strong>GRSNC</strong>)Membre <strong>de</strong> l'Équipe FCAR - Plasticité synaptique dans les réseaux <strong>de</strong> neuronesFormation / TrainingB.A., Université Laval, 1960B.Sc., Université Laval, Biologie, 1964Ph.D., Washington University, Neurobiologie, 1968Postdoctorale, New York University, School of Medicine, Neurobiologie, 1968-1970Orientation <strong>de</strong> la recherche•Étu<strong>de</strong> <strong>de</strong>s mécanismes cellulaires et moléculaires du comportement et <strong>de</strong> ses modifications par l'apprentissage.•Neurobiologie <strong>de</strong>s invertébrés.Principaux projets en cours:•Étu<strong>de</strong>s et comparaisons <strong>de</strong>s mécanismes cellulaires <strong>de</strong> la mémoire à court-terme et à long-terme chez le mollusque marin aplysie.•Étu<strong>de</strong> <strong>de</strong> la plasticité synaptique du système nerveux central.Research orientation•Cellular and molecular mechanisms of behavior and its modifications by learning.•Invertebrate neurobiology.Current research projects:•Comparative studies of cellular mechanisms of short term and long term memory in the animal mo<strong>de</strong>l Aplysia.•Synaptic modulation in the central nervous system.Publications choisies/Selected publicationsManseau, F., Fan, X., Hueftlein, T., Sossin, W. S. et Castellucci, V. F. Ca2+-indépendant PKC APL II mediates the serotonin induced facilitation at<strong>de</strong>pressed Aplysia sensorimotor synapses. J. Neurosci. 21:1247-1256, 2001.Barbas, D., Zappulla, J. P., Angers, S., Bouvier, M., Castellucci, V. F. et DesGroseillers, L. Functional characterization of a novel serotoninreceptor (5-HTAF2) expressed in the CNS of Aplysia californica. J. Neurochem. 80: 335-345, 2002.Barbas, D., DesGroseillers, L., Castellucci, V. F., Carew, T.J. and Marinesco, S. Multiple serotonergic mechanisms contributing to sensitization inAplysia: evi<strong>de</strong>nce for diverse serotonin receptor subtypes. Learning and Behavior 10: 373-386, 2003.Nakhost, A., Houeland, G., Castellucci, V. F. and Sossin, W.S. Differential regulation of transmitter release by alternative splice forms of synaptotagminI. J. Neurosci. 23: 6238-6244, 2003.Nakhost, A., Houeland, G., Blandford, V. E., Castellucci, V. F. and Sossin, W. S. I<strong>de</strong>ntification and characterization of a novel C2B splice variant ofsynaptotagmin I. J.Neurochem 89: 354-363, 2004.Barbas, D., Campbell, A., Castellucci, V. F. and DesGroseillers, L. Comparative localization of two serotonin receptors and sensorin in the centralnervous system of Aplysia californica. Journal of Comparative Neurology 490: 295-304, 2005Barbas, D., Zappula, J.P., Angers, S., Bouvier,M., Byrne J.H., Castellucci, V.F. and DesGroseillers L. An Aplysia Dopamine1-like receptor: molecular andfunctional characterization. J.Neurochem 96: 414-427, 2006.Page 24

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