BULETINUL ИЗВЕСТИЯ JOURNAL

Buletinul AŞM. Ştiinţele vieţii. Nr. 3(318) 2012
Рефераты
UDC: 579.61:616+615.33:579.8
DETECTION OF ENTEROBACTERIA RESISTANCE MARKERS FOR
ANTIBIOTIC. Burduniuc Olga, Cojocaru R., Balan Greta, Spînu C., Roşcin Iu. // Buletinul
Academiei de Ştiinţe a Moldovei. Ştiinţele vieţii.. 2012, No 3 (318), p. 151-158.
Antibiotic resistance is a complex, multifactorial problem, and is of great importance to
public health, requires a complex analysis, and implementation of specifi c measures at different
levels. The rapid growth of resistant strains of Enterobacteriaceae imposes the need for
implementation of rapid and specifi c techniques of molecular biology. The studies emphasize
that the prevalence of urinary tract infections caused by Escherichia coli, which has the resistance
profi le extended-spectrum beta-lactamases type is 5.3%, and the prevalence of intestinal carriage
- 15%. Detection of E.coli strains such as CTX-M-14 of the phylogenetic group B2, which have
a high potential for the spread in the community, can lead to the appearance of resistance and
diffi culties in the treatment of patients. Surveillance and monitoring of E.coli strains producing
CTX-M plays an important role in the selection of treatment and reviewing empirical treatment
protocols.
18 references, 3 fi gures.
Keywords: Resistance to antibiotics - monitoring - phenotype - Molecular biology - extended
spectrum beta-lactamases - CTX-M.
Received January 26, 2012
UDC: 582.28:577.153.2+54.386
COORDINATIVE COMPOUNDS OF MOLYBDENUM AND VANADIUM AS
POSSIBLE STIMULATORS OF EXTRACELLULAR CELLULASES BIOSYNTHESIS
BY MICROMYCETES Penicillium expansum CNMN FD 05 C. Chilochi A., Tyurina J.,
Bologa O., Clapco S., Lablyuk S., Pasha L., Coropchanu E., Rija A. // Buletinul Academiei de
Ştiinţe a Moldovei. Ştiinţele vieţii.. 2012, No 3 (318), p. 158-165.
The effect of coordinative compounds of molybdenum and vanadium on the biosynthesis
of cellulosolytic enzymatic complex (endoglucanases, celobiohydrolases, β-glucosidases) of
the fungal strain Penicillium expansum CNMN FD 05C was investigated. It was established
that complexes of molybdenum, which contain amino acids in its composition, have a neutral
effect on the activity of endoglucanases, inhibit celobiohydrolases (80-90%) and stimulate the
activity of β-glucosidases. Among the most effective stimulators of β-glucosidases synthesis,
the complex MoO 2 (ac.ac.)Gly may be mentioned, that increases the enzymatic activity by 47.8-
67.0%. This complex can be used to obtain an enzymatic preparation with a high content of
β-glucosidases. The metal complex (NH 4 ) 2 VO 3 Gly stimulates the activity of enzymes of the
cellulosolytic complex of the fungi Penicillium expansum CNMN FD 05C, increasing the
endogluconasic activity by 45%, cellobiohydrolasic by 32% and β-glucosidasic by 40%.
16 references, 3 tables, 3 fi gures.
Key words: Penicillium expansum - metal complex – endoglucanases – cellobiohydrolases
- β-glucosidases
Received October 22, 2012
UDC: 576.8
STANDARTIZATION OF THE CONSERVATION METHOD FOR BACTERIA
STRAINS FROM THE NATIONAL COLLECTION OF NONPATHOGENIC
MICROORGANISMS. II. STANDARTIZATION OF THE CONSERVATION
METHOD FOR BACILLUS STRAINS FROM THE NATIONAL COLLECTION OF
NONPATHOGENIC MICROORGANISMS. Tolochikina S., Slanina V., Boortseva S.,
Postolaky O., Syrbu T., Lupashku L., Stepanov V. // Buletinul Academiei de Ştiinţe a Moldovei.
Ştiinţele vieţii.. 2012, No 3 (318), p. 165-172.
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