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Forensic Pathology for Police - Brainshare Public Online Library

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Emboli 547<br />

Fig. 21.8 Decomposed sclera (white part of eyes)<br />

Pulmonary Thromboemboli<br />

Thromboemboli typically arise as thrombi (blood clots) within the deep veins of<br />

the legs, although occasionally they involve the pelvic veins, or even within the<br />

dural sinuses. When thrombi occur in these deep veins, the condition is called “deep<br />

venous thrombosis” (DVT). Persons are at increased risk <strong>for</strong> developing DVT in<br />

a variety of situations, including various hereditary conditions that predispose to<br />

clotting (factor V leiden mutations, protein S deficiency, protein C deficiency), obesity,<br />

pregnancy, any condition that leads to decreased mobility, and trauma. If a<br />

DVT breaks away from the blood vessel wall, it can travel (“embolize”) through<br />

the venous system, into and through the right side of the heart, and then become<br />

lodged within the pulmonary arteries (Fig. 21.9). If the thromboembolus is large<br />

enough, it can cause sudden collapse and death. Such thromboemboli are usually<br />

Fig. 21.9 Pulmonary embolism characterized by blood thrombi (clots) blocking the pulmonary<br />

artery

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