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Forensic Pathology for Police - Brainshare Public Online Library

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Therapy-Related Deaths 585<br />

nature, or related to a non-traumatic, non-acute, natural physiologic response to<br />

appropriately-implemented therapy. In contrast, if the intervention that contributed<br />

to death is a true mistake or error, or if it is unexpected, acute, and temporally related<br />

to the intervention, associated with mechanical failure of a medical device, or traumatic<br />

in nature (Fig. 21.30), then the MOD ruling should be “accident.” Of note<br />

is the fact that in a few jurisdictions within the United States, the MOD choices<br />

include a sixth option: “therapeutic complication.” Un<strong>for</strong>tunately, such an option is<br />

not available in most jurisdictions.<br />

Fig. 21.30 A case where<br />

chest tube placement<br />

inadvertently penetrated the<br />

lung, causing injury<br />

Examples of cases where an intervention is believed to be contributory to death,<br />

but the MOD is ruled “natural,” include the following: an elderly patient with underlying<br />

heart and lung disease who develops post-operative pneumonia following<br />

otherwise successful surgery; an obese patient who develops post-operative deep<br />

venous thrombosis and dies suddenly from a pulmonary embolism, one week after<br />

otherwise successful knee replacement surgery; a patient with cancer who develops<br />

a severe infection and dies, following intensive chemotherapy. It should be noted<br />

that in jurisdictions where “therapeutic complication” is available on the death certificate,<br />

these cases can be ruled in this manner instead of “natural,” but when no<br />

such option exists, it is appropriate to rule them as “natural.” Examples of cases<br />

where an intervention is the cause or a contributory cause to death and the MOD ruling<br />

is appropriately considered “accident” include the following: a fatal transfusion<br />

reaction related to a clerical error; a patient dying from infusion of an intravenous<br />

line with the wrong medication; a patient dying from an air embolism during laparoscopic<br />

surgery; a patient dying from extensive internal hemorrhage initiated from a<br />

femoral artery per<strong>for</strong>ation, per<strong>for</strong>med <strong>for</strong> a cardiac catheterization procedure; death<br />

from peritonitis following dislodgement of a feeding tube; an idiosyncratic reaction

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