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impaginato piccolo - Società Italiana di Parassitologia (SoIPa)

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<strong>Parassitologia</strong> 50: 99-101, 2008<br />

Availability of insecticidal molecules to control Aedes<br />

albopictus (Skuse)<br />

A. Baseggio<br />

I.N.D.I.A. INDUSTRIE CHIMICHE S.p.A, Technical Assistance<br />

Introduction<br />

Abstract. Following the implementation of the Directive 98/8/CE a few changes in the availability of insecticidal<br />

molecules to control Ae. albopictus have been outlined. Available products for larvicidal treatments<br />

will predominantly be based upon two growth regulators (<strong>di</strong>flubenzuron and pyriproxyfen). For the control<br />

of the adult forms there will mostly be active ingre<strong>di</strong>ents belonging to the pyrethroid group. Importance of<br />

surveillance for the onset of tolerance or resistance phenomena.<br />

Keywords: Ae. Albopictus, Italy, insecticides, availability.<br />

The current availability of insecticidal molecules to control<br />

Aedes albopictus in Italy and the other European<br />

Community member states will undergo a reduction in<br />

both the number of active ingre<strong>di</strong>ents and commercial<br />

formulations that can be used. The reduction will affect<br />

both professional pest controllers as well as private consumers.<br />

The reason for this reduction is the implementation<br />

of the review enforced by the Directive 98/8/EC<br />

known as the “Biocidal Products Directive”.The first<br />

“practical” consequences of this <strong>di</strong>rective, with regards<br />

to the availability of insecticidal active ingre<strong>di</strong>ents, are<br />

included in the Commission Regulation (EC) N°<br />

2032/2003 and have brought about, amongst other<br />

things, the ban on the use of triclorphon active ingre<strong>di</strong>ent,<br />

used in Italy for the production of slow-release<br />

tablets registered for the treatment of stagnant water for<br />

mosquito larvae in general. A more important further<br />

effect is the ban on the use of temephos active ingre<strong>di</strong>ent<br />

as of the 31 st March 2008 (Ministry of Health<br />

decree 24/10/2007). Over the last 20 years temephos<br />

has been the most widely used active ingre<strong>di</strong>ent for the<br />

production of larvicidal formulations. This active ingre<strong>di</strong>ent<br />

was available in a wide variety of formulations:<br />

emulsifiable concentrates, water-based microemulsions<br />

and slow-release tablets.From the 22 th August 2008<br />

(G.U.U.E. L 216/17 of the 21.08.2007) malathionbased<br />

products can no longer be used (from this date<br />

the use of chlorpyrifos-ethyl and chlorpyrifos-methyl<br />

will also cease but this active ingre<strong>di</strong>ent is thought to<br />

have only been used for adulticidal treatments against<br />

Ae. albopictus in a few areas of central and southern<br />

Italy due to its high resistance to thermal degradation).<br />

The ban on malathion use could have a greater impact<br />

than that of chlorpyrifos-ethyl and methyl, particularly<br />

for the use made by professional pest controllers.<br />

Correspondence: Alberto Baseggio,<br />

I.N.D.I.A. Industrie Chimiche S.p.A. - Via Nona Strada, 55<br />

35129 Padova, Italy<br />

Tel + 39 049 8076144, Fax + 39 049 8076146,<br />

e-mail: a.baseggio@in<strong>di</strong>aprodotti.com<br />

The amount of malathion sold by I.N.D.I.A. S.p.A. during<br />

the 2007 season alone to professional pest controllers<br />

and public pest control services against mosquitoes<br />

amounts to approximately 15,000 litres of commercial<br />

formulations.The insecticidal molecules that<br />

are very likely to be authorised for use (but confirmation<br />

will only come once the dossiers submitted for<br />

review have been approved) following the review<br />

enforced by the BPD are:<br />

1) For larvicidal treatments:<br />

(i) Bacillus thuringiensis var. Israelensis serotype H<br />

14: (ii)Bacillus sphaericus (currently unavailable in<br />

Italy); (iii) Diflubenzuron (chitin synthesis inhibitor);<br />

(iv) Pyriproxyfen (juvenile hormone analogue):<br />

In the summer of 2008 the experimentation of<br />

Spinosad-based formulations will also begin in Italy.<br />

Commercial products are expected to become available,<br />

for mosquito larvae control, from 2010-2011.<br />

At the moment the availability of S-methoprene growth<br />

regulator doesn’t appear to be certain. The dossier<br />

required by the Biocidal Products Directive will be submitted<br />

but probably without envisaging use in waterways.By<br />

examining the applicative con<strong>di</strong>tions that characterise<br />

the larvae-control campaign treatments against<br />

Ae. albopictus, and based upon a few experiences collected<br />

from the public services who coor<strong>di</strong>nate the Ae.<br />

albopictus control treatments in their territory, a few<br />

simple conclusions can be drawn.The use of B. thur.<br />

var. israelensis-based formulations can be helpful for<br />

citizens who wish to carry out their own larvicidal<br />

treatments, but the larval control only becomes significant<br />

if the commercial formulation is applied at least<br />

weekly and if, at the same time, the larval development<br />

bree<strong>di</strong>ng grounds on public land are subject to careful<br />

control.For the public services who need to plan the<br />

treatment of thousands (or tens of thousands) of micro<br />

bree<strong>di</strong>ng grounds present on public land (mostly road<br />

drainage grates of various shapes and sizes) the use of<br />

products marked by reduced persistence is not economically<br />

sustainable, not due to the cost of the product but<br />

due to the cost of the manpower necessary for its application.<br />

Diflubenzuron and pyriproxyfen are currently<br />

extremely efficient against Ae. albopictus. In particular,

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