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impaginato piccolo - Società Italiana di Parassitologia (SoIPa)

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100<br />

pyriproxyfen is twice as biologically active as <strong>di</strong>flubenzuron,<br />

and therefore commercial formulations containing<br />

pyriproxyfen can be used that release smaller<br />

amounts of active ingre<strong>di</strong>ent into the environment.<br />

Usually pyriproxyfen-based commercial products contain<br />

a quarter of the active ingre<strong>di</strong>ent contained in<br />

<strong>di</strong>flubenzuron-based products whilst provi<strong>di</strong>ng similar<br />

persistence.Sprea<strong>di</strong>ng the larvicidal treatments over<br />

intervals longer than 3-4 weeks results in a risk of<br />

Composition Composition Usage rates taken from technical data sheets and referring<br />

to a street manhole with 40 litres water<br />

Pyriproxyfen 4%<br />

Diflubenzuron 15%<br />

A. Baseggio - Mosquitoes control products<br />

Water microemulsion<br />

Suspension concentrate<br />

The the list of insecticidal active ingre<strong>di</strong>ents for<br />

which companies are currently producing the<br />

review dossiers required by the BPD shows that<br />

underestimating the operative structure (i.e. the number<br />

of operators occupied in the territory) and therefore<br />

in the inability to manage unplanned treatments,<br />

for example after heavy rainfall. In Japan it has been<br />

observed that Ae. albopictus can develop resistance to<br />

pyriproxyfen and <strong>di</strong>flubenzuron but it is a long process<br />

(Kasai S. et al, 2007, J. Med. Entomol. 44 (5): 822-<br />

829).<br />

2) For adulticidal treatments<br />

Table 1. comparison between the usage rates of common liquid larvicides containing IGR active ingre<strong>di</strong>ents<br />

Etofenprox is a phenoxyderivative substance marked<br />

by a mode of action similar to that of pyrethroids but<br />

with a particularly reduced acute toxicity (LD50 acute<br />

oral rat = 42880 mg/kg; acute dermal > 2140 mg/kg;<br />

0.25 ml of product per manhole<br />

0.28 ml of product per manhole<br />

pyrethroids will mainly be available in the future<br />

(Table 2)<br />

Etofenprox has interesting toxicological characteristics;<br />

Table 2. list of pyrethroids whose dossiers will most likely be submitted for review; synthetic data on acute toxicity.<br />

Active ingre<strong>di</strong>ent LD50 acute<br />

oral rat mg/kg<br />

d-Phenotrin<br />

Permethrin<br />

Deltamethrin (in water)<br />

Tetramethrin<br />

d-Tetramethrin<br />

Transfluthrin<br />

Cypermethrin<br />

Deltamethrin (in naphta)<br />

Alpha-cypermethrin<br />

Esbiothrin<br />

Natural pyrethrin<br />

Cyphenothrin<br />

Esfenvalerate<br />

Lambda-cyalothrin<br />

Bifenthrin<br />

I = irritating<br />

Inhalation toxicity (4h) =5900 mg/m 3)<br />

Average usage rates of a few insecticides available on<br />

the market:<br />

Two OP active ingre<strong>di</strong>ents will also be available in ad<strong>di</strong>-<br />

Composition (%) Formulation type Average rates for adult mosquitocontrol<br />

Cypermethrin 10<br />

Tetramethrin 2<br />

Piperonyl Butoxide 5<br />

Permethrin 15<br />

Tetramethrin 2.5<br />

Piperonyl Butoxide 5<br />

Deltamethrin 1<br />

Esbiothrin 2.5<br />

Piperonyl Butoxide5<br />

Etofenprox 10<br />

Piperonyl Butoxide 20<br />

> 10000<br />

6000<br />

> 5000<br />

> 5000<br />

> 5000<br />

> 5000<br />

250 – 4150<br />

800<br />

474<br />

> 432<br />

570-150<br />

318<br />

88,5<br />

79<br />

> 53,4<br />

Water microemulsion<br />

Water microemulsion<br />

Suspension concentrate<br />

Water microemulsion<br />

LD50 acute<br />

dermal mg/kg<br />

> 10000<br />

> 2500<br />

> 2000<br />

> 5000<br />

> 5000<br />

> 5000<br />

> 4820<br />

> 2000<br />

> 2000<br />

> 2000<br />

1500<br />

> 5000<br />

> 5000<br />

696<br />

> 2000<br />

LC50 Inhalation<br />

toxicity (4h)<br />

> 2100 mg/l<br />

> 685 mg/l<br />

> 22 mg/l<br />

2,73 mg/l<br />

> 1,18 mg/l<br />

> 0,513 mg/l<br />

> 25 mg/l<br />

> 22 mg/l<br />

> 0,32 mg/l<br />

2,63 mg/l<br />

3,4 mg/l<br />

> 1,85 mg/l<br />

> 0,48 – 0,57 mg/l<br />

0,06 mg/l<br />

> 0,8 mg/l<br />

0.5%<br />

0.8%<br />

0.75%<br />

0.5%<br />

Properties<br />

Non photostable<br />

Photostable<br />

Photostable I<br />

Non photostable<br />

Non photostable<br />

Non photostable<br />

Photostable, I<br />

Photostable, I<br />

Photostable<br />

Non photostable<br />

Non photostable<br />

Photostable<br />

Photostable, I<br />

Photostable, I<br />

Photostable

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