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Sick and Tired: Understanding and Managing Sleep Difficulties in ...

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emotional problems, <strong>in</strong>creased pa<strong>in</strong> <strong>and</strong> poor general health. A greater underst<strong>and</strong><strong>in</strong>g of<br />

the factors that may be caus<strong>in</strong>g the night-time awaken<strong>in</strong>gs <strong>and</strong> perceptions of poor sleep<br />

quality, therefore requires further <strong>in</strong>vestigation to <strong>in</strong>form possible treatment<br />

<strong>in</strong>terventions. Case-control studies provide stronger evidence of cause-effect<br />

associations compared to cross-sectional studies <strong>and</strong> also enable comparison with<br />

controls to be made, thus <strong>in</strong>dentify<strong>in</strong>g significant differences that may affect the<br />

outcome under <strong>in</strong>vestigation. A case-control study exam<strong>in</strong><strong>in</strong>g the potential factors that<br />

may <strong>in</strong>fluence sleep quality <strong>in</strong> patients with FMS was therefore selected for Study Two<br />

of this thesis.<br />

78

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