Computational tools and Interoperability in Comparative ... - CBS
Computational tools and Interoperability in Comparative ... - CBS
Computational tools and Interoperability in Comparative ... - CBS
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74 Tools for Comparison of<br />
Bacterial Genomes<br />
T. M. Wassenaar 1,2 . T. T. B<strong>in</strong>newies 1,3 . P. F. Hall<strong>in</strong> 1 . D. W. Ussery 1, *<br />
1<br />
Center for Biological Sequence Analysis, Technical University of<br />
Denmark, Kgs. Lyngby, Denmark<br />
*dave@cbs.dtv.dk<br />
2<br />
Molecular Microbiology <strong>and</strong> Genomics Consultants, Zotzenheim,<br />
Germany<br />
3<br />
Roche Diagnostics Ltd., Advanced Systems Group, Global Platforms &<br />
Support, Rotkreuz, Switzerl<strong>and</strong><br />
1 Introduction . . . . . . ..................................................................4314<br />
2 Genomic DNA Sequence Comparisons . ...........................................4314<br />
3 Visualization of Genomic Data: The Genome Atlas ..............................4317<br />
4 Whole Genome Alignment Methods . . . . ...........................................4319<br />
5 Compar<strong>in</strong>g the Cod<strong>in</strong>g Fraction of Genomes . . . . . . . . ..............................4321<br />
6 Codon Usage Comparisons . . . . .....................................................4322<br />
7 Prote<strong>in</strong> Sequence Comparisons . . . . . . . . . ...........................................4322<br />
8 Gene Synteny <strong>and</strong> Genome Isl<strong>and</strong>s . . . . . ...........................................4325<br />
9 M<strong>in</strong>imal Information About a Genome Sequence . . . ..............................4325<br />
10 Research Needs . . . ..................................................................4325<br />
K. N. Timmis (ed.), H<strong>and</strong>book of Hydrocarbon <strong>and</strong> Lipid Microbiology, DOI 10.1007/978-3-540-77587-4_337,<br />
# Spr<strong>in</strong>ger-Verlag Berl<strong>in</strong> Heidelberg, 2010