W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

D is of formula
wherein R 2 may be hydroxyl (-OH), alkoxy (-0-R'), wherein R' is a C1-C8 linear
or branched, saturated or unsaturated alkyl chain and is preferably a methoxy
group (-OCH 3 ), or R 2 is -N-R 3 2 , wherein each R3 may be independently H, a
C1-C8 linear or branched, saturated or unsaturated alkyl chain, optionally
substituted with an A group, wherein the A group may be a C3-C6 saturated or
partially unsaturated cyclic- or heterocyclic ring or a C5-C6 aromatic or
heteroaromatic ring, which cyclic or heterocyclic, aromatic or heteroaromatic
ring may be optionally substituted at any available position with one or more of
hydroxyl (-OH), C1-C8 linear or branched, saturated or unsaturated alkyl chain,
C1-C8 linear or branched, saturated or unsaturated alkoxy carbon chain,
hydroxyalkyl, such as hydroxymethyl (-CH 2 OH), amino (-NH ), thiol (-SH), nitro
(-NO 2 ) , carboxy (-COOH), wherein preferred A groups are cyclopropane,
cyclopentane, cyclohexane, phenyl, thiazole, imidazole, oxazole; or wherein R 3
may be any of the A groups above disclosed; and wherein
M
M is -(O-CH 2 -CH 2 -) n -Q o r -(0-CH 2 -CH 2 -CH 2 -) n -Q, wherein Q is
H
selected from — — , -S- or -O- , which is bound to the dendron W scaffold