W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel
W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel
W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
wherein aj is 32 and J is a third generation 2,2'-bis(methoxyol)propanoic acid<br />
(bis-MPA) based dendrimerforthe treatment and/or prevention of HIV (Human<br />
Immunodeficiency Virus), Dengue, Ebola, Hepatitis C, SARS and<br />
Mycobacterium tuberculosis infections.<br />
For the purposes of a forth embodiment of the present invention, the disclosed<br />
compounds may be formulated in a suitable effective amount together with<br />
suitable pharmaceutically acceptable excipients according to the specific form<br />
of administration and/or additives selected in the group comprising diluent,<br />
solvents, bulking agents, fillers, reological modifier, stabilizers, binders,<br />
lubricants, disintegrant, preservatives, pH adjusting agents, buffers,<br />
antioxidant, chelating agents, plasticizer, polymers, emulsifiers, edulcorants,<br />
flavoring agents, alone or in combination thereof, to give a pharmaceutical<br />
preparation as per a further embodiment of the invention.<br />
The preparations of the present invention may be administered by various<br />
route of administration, such as, for instance, oral, including buccal or<br />
sublingual administration; rectal; nasal; transdermal; vaginal; or parenteral,<br />
including subcutaneous, intramuscular, intravenous or intradermal route or<br />
topically.<br />
In particular, for oral administration, they can be prepared in the form of hard or<br />
soft capsules, tables, powders or granules; solutions syrups or suspensions in<br />
aqueous or non-aqueous liquids; edible foams or whips; or either oil-in-water or<br />
water-in-oil liquid emulsions. Alternatively, for nasal administration sprays or