19.08.2013 Views

W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

wherein R 2 may be hydroxyl (-0H), alkoxy (-0-R'), wherein R' is a C1-C8 linear<br />

or branched, saturated or unsaturated alkyl chain and is preferably a methoxy<br />

group (-OCH 3 ), or R 2 is -N-R 3 2 , wherein each R3 may be independently H, a<br />

C1-C8 linear or branched, saturated or unsaturated alkyl chain, optionally<br />

substituted with an A group, wherein the A group is a C3-C6 saturated or<br />

partially unsaturated cyclic- or heterocyclic ring or a C5-C6 aromatic or<br />

heteroaromatic ring, optionally substituted at any available position with one or<br />

more of hydroxyl (-OH), C1-C8 linear or branched, saturated or unsaturated<br />

alkyl chain, C1-C8 linear or branched, saturated or unsaturated alkoxy carbon<br />

chain, amino (-NH 2 ) , thiol (-SH), nitro (-NO 2 ), carboxy (-COOH); or R 3 is an A<br />

group as above defined; and M may be<br />

H<br />

wherein Q is selected from — N — , -S- or -O- and is linked to the J scaffold<br />

through a Y linker and n is 1 to 3; or wherein R2 is -N-R 3 2 as above disclosed<br />

and M is -(O-CH 2 -CH 2 -) n -Q or -(O-CH 2 -CH 2 -CH 2 -) n -Q, wherein Q, Y and n are<br />

as above disclosed, wherein each R 3 may be independently H, a C1-C8 linear

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!