W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel
W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel
W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel
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wherein R 2 , Q and n have the same meaning as above disclosed.<br />
In particular, in a preferred embodiment, said J dendrimer based on 2,2'-<br />
bis(methoxyol)propanoic (bis-MPA) is a first or second generation or higher<br />
generation bis(methoxyol)propanoic (bis-MPA) based dendrimers (see, for<br />
instance, at Fig. 12).<br />
According to the above, a preferred compound within formula (Ib) is compound<br />
15 below reported<br />
prepared according to the following Example 3, wherein R 1 is H, R 2 is methoxy<br />
H<br />
(-OCH 3 ), R is H, n is 1, Q is — — and it is linked to Y, which is a succinic<br />
acid residue and the J scaffold is a third generation 2,2'-<br />
bis(methoxyol)propanoic (bis-MPA) based dendrimer.<br />
Alternatively, the dendrimer scaffold J may be a poly(amidoamine) (PAMAM)<br />
based dendrimer (see, for instance, at Fig. 13).<br />
15