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W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

W0 2011/000721 A1 I||||||||||||||||||||||||||||||||||||||||||||||||||||||||| - Questel

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wherein R 2 , Q and n have the same meaning as above disclosed.<br />

In particular, in a preferred embodiment, said J dendrimer based on 2,2'-<br />

bis(methoxyol)propanoic (bis-MPA) is a first or second generation or higher<br />

generation bis(methoxyol)propanoic (bis-MPA) based dendrimers (see, for<br />

instance, at Fig. 12).<br />

According to the above, a preferred compound within formula (Ib) is compound<br />

15 below reported<br />

prepared according to the following Example 3, wherein R 1 is H, R 2 is methoxy<br />

H<br />

(-OCH 3 ), R is H, n is 1, Q is — — and it is linked to Y, which is a succinic<br />

acid residue and the J scaffold is a third generation 2,2'-<br />

bis(methoxyol)propanoic (bis-MPA) based dendrimer.<br />

Alternatively, the dendrimer scaffold J may be a poly(amidoamine) (PAMAM)<br />

based dendrimer (see, for instance, at Fig. 13).<br />

15

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