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NEW PRODUCTS http://science.labvelocity.com Albumin and IgG Removal Albumin and gammaglobulin (IgG) can constitute more than 50% of total serum proteins, obscuring other proteins and making the resolution of low-abundant proteins difficult. Two new kits, one antibody-based and one dye-based, efficiently remove albumin and IgG from samples.The ProteoSeek Antibody Based Albumin/IgG Removal Kit contains an immobilized anti-IgG/anti-albumin gel for the removal of human serum albumin and all major subclasses of IgG from human serum, plasma, or spinal fluids. The dye-based ProteoSeek Albumin/IgG Removal Kit contains a mixed bed matrix of immobilized cibacron blue and high-capacity immobilized protein A and provides an efficient, economical method for depleting excess abundant proteins while enriching the lower molecular weight proteins, peptides, and other small components. Pierce For information 815-968-0747 www.piercenet.com DNA Damage System The Comet Assay IV is an interactive video-based software system that measures the DNA damage detected using single-cell gel electrophoresis. Using a high-definition video camera attached to a microscope, Comet Assay IV provides real-time cell scoring by transferring a live video image to a computer screen with no time lag. The comet assay is one of the standard methods of assessing DNA damage and uses fluorescent microscopy to examine it at the single-cell level in a wide range of applications, including genotoxicity testing, ecotoxicology, clinical diagnostics, food processing and nutrition, mechanistic research, and health and safety testing. The system can be incorporated into existing protocols and data can be saved to Microsoft Excel or an Oracle database. Perceptive Instruments For information +44 (0)1440 730773 www.perceptive.co.uk Quantitative Proteomics Software Proteineer-LC 1.1 is a unique liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) based quantitative proteomics solution. Protein- Scape 1.3 is new bioinformatics software. Stable isotope labeling experiments and userdefined isotopic labels are fully supported in these new software releases. The Proteineer software suite extends the existing workflow support from two-dimensional gel to LC- MS/MS-based protein identification and quantitation using Bruker Daltonics’ Ultraflex II matrix-assisted laser desorption ionization-time of flight and HCTultra ion trap mass spectrometers. Bruker Daltonics For information 978-667-9580 www.bruker-biosciences.com For more information visit GetInfo, Science's new online product index at http://science.labvelocity.com From the pages of GetInfo, you can: • Quickly find and request free information on products and services found in the pages of Science. • Ask vendors to contact you with more information. • Link directly to vendors' Web sites. Stackable Shaking Cabinets The Certomat BS-1 line of high-capacity, stackable environmental shaking cabinets has been redesigned for improved user-friendliness and longevity. Requiring less than 10 square feet of floor space, up to three cabinets can be stacked without any reduction in shaking speeds. The interior chamber can hold up to six-liter Erlenmeyer flasks.All key parameters are programmable though a digital controller. Clean-up of spills is easy because of a hygienic, polished stainless steel interior and removable spill tray. Sartorius For information 800-258-9000 www.sartorius-bbi-systems.com Electronic Pipettors The line of Biopette E Electronic Pipettors has been expanded to 12 models available in single-, 8-, and 12-channel configurations. The new 8-channel and 12-channel, 1200-μl instruments are well-suited for efficient pipetting into 96-well plates. Pipetting modes include multiple dispensing, mixing, sequential dispensing, sequential aspiration, and serial dilution. The instruments feature a lightweight, ergonomic design and fully motorized piston drive to reduce the potential for repetitive stress injury. Labnet International For information 888-522-6381 www.labnetlink.com Membrane Protein Plates CrystalQuick Plus combines the optical properties of a flat crystallization well bottom with superior surface features, rendering a format especially conducive to crystallography of cell membrane proteins. The hydrophobic plate surface effectively prevents drop deformation, even when surface-tension–reducing substances such as detergents or ethanol are contained within. In addition, the hydrophobic surface significantly reduces meniscus formation of reservoir screening solutions, thereby minimizing the risk for screening solution to spread from the reservoir into the crystalization well. CrystalQuick Plus permits screening of up to 288 crystallization setups per plate. Each screening reservoir contains an elevated platform with three square, flat bottom crystallization wells to perform multiple sitting drop vapor diffusions within a 96-well framework. Designed to facilitate high-throughput protein crystallography in automated system, the plates enable the investigation of optimal crystal growth conditions and subsequent x- ray diffraction at reduced cost. Greiner Bio-One For information 800-884-4703 www.gbo.com/bioscience Literature Endogen Applications Handbook and Catalog 2005/2006 is an 82-page publication with technical sections on enzyme-linked immunosorbent assays, Searchlight multiplex assays and custom array development, enzyme-linked immunospot kits, and primer sets. It also features information for recombinant proteins, recombinant active kinases, antibodies, and supporting reagents. Pierce For information 815-968-0747 www.piercenet.com Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and government organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials.Endorsement by Science or AAAS of any products or materials mentioned is not implied.Additional information may be obtained from the manufacturer or supplier by visiting www.science.labvelocity.com on the Web, where you can request that the information be sent to you by e-mail, fax, mail, or telephone. www.sciencemag.org SCIENCE VOL 309 2 SEPTEMBER 2005 1591
Q: Where can I present my research so that it is seen by aninternational audienceof premier leaders in science, technology, and engineering? A: At the 2006 AAAS Annual Meeting, 16–20 February, St. Louis, Missouri. It’s the world’s foremost interdisciplinary forum. Call for Posters Submission Deadline: 7 November 2005 The AAAS Poster Session provides the opportunity for individuals topresent their research and offers anexcellent venuefor extended informal discussion withmeeting attendees. All posters will bepeer-reviewed. Accepted posters will belisted in the 2006 AAAS Annual Meeting Poster Book. Especially for students: Students can compete to earn travel assistancegrants.FREE registration opportunities are also available. Learnmore: www.aaasmeeting.org/student. Submission opens 6 September 2005. For guidelines and details, visit: www.aaasmeeting.org
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DISEASE: A 20-YEAR RIDDLE Well that
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New England Biolabs - an uncommon p
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CVS and amniocentesis are 99% accur
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