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Research projects (13000 - 13500 of 26984)

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Grant: Unraveling and treating impaired pain inhibition during exercise in patients with Myalgic<br />

Encephalomyelitis/Chronic Fatigue Syndrome: a clinical experiment targeting brain neurotransmission.<br />

Vrije Universiteit Brussel<br />

Abstract: In a previous MERUK-funded study, we showed that pain inhibition during exercise is impaired in patients with myalgic encephalomyelitis /<br />

chronic fatigue syndrome. This finding is in line with our previous findings <strong>of</strong> delayed pain inhibition at rest in response to heat pain. It becomes<br />

more and more clear that the lack <strong>of</strong> pain inhibition accounts in part for various symptoms at rest and following exercise in particular ('postexertional<br />

malaise'). However, the mechanisms behind the lack <strong>of</strong> pain inhibition during exercise remain to be revealed.<br />

The mechanisms responsible for impaired pain inhibition in response to exercise in people with MF/CFS might be crucial in developing appropriate<br />

drug treatments to prevent post-exertional malaise. The present study aims at examining whether a drug targeting brain neurotransmission is able<br />

to decrease post-exertional malaise in patients with inhibitory pathways.<br />

In addition, the recognition <strong>of</strong> ME/CFS as a severe illness remains an important issue. Therefore, the present study proposal aims at comparing the<br />

results obtained in ME/CFS patients with those obtained in a patient group with an established medical diagnosis characterized by chronic pain <strong>of</strong><br />

peripheral rather than central origin. To compare the findings in ME/CFS with those obtained from RA patients, the project includes 2 triple blind,<br />

randomized controlled, cross-over studies.<br />

Organisations:<br />

• Human Physiology and Special Physiology <strong>of</strong> Physical Education<br />

<strong>Research</strong>ers:<br />

• JO NIJS<br />

Characterization and role <strong>of</strong> dysbiosis in the pathogenesis <strong>of</strong> inflammatory bowel disease<br />

K.U.Leuven<br />

Abstract: No English Abstract<br />

Organisations:<br />

• Translational <strong>Research</strong> in GastroIntestin<br />

<strong>Research</strong>ers:<br />

• Jan Verhaegen<br />

• Séverine Vermeire<br />

• Paul Rutgeerts<br />

• Kathleen Machiels<br />

Reducing microbial data entropy through workflow management<br />

Ghent University<br />

Abstract: The bioinformatics landscape today witnesses the emergence <strong>of</strong> web services andworkflows as a publishing interface for data and<br />

computation. Following thisline <strong>of</strong> thought, a series <strong>of</strong> organism-centric web services and workflows aredeveloped based on the integration efforts<br />

conducted in the framework <strong>of</strong> theStrainInfo bioportal.<br />

Organisations:<br />

• Departement <strong>of</strong> Applied mathematics and computer science<br />

<strong>Research</strong>ers:<br />

• Peter Dawyndt<br />

The Other Flood: Vulnerability and Resilience<br />

Ghent University<br />

Abstract: Floods can have very serious consequences. In order to reduce the impacts <strong>of</strong> floods, they need to be considered from a broad<br />

perspective. A comprehensive and integrative approach combines the technical measures with the economic, ecological (environmental) and social<br />

aspects. FLOTHER lays the emphasis on social aspects, associated with floods. It will investigate how vulnerable and resilient people are and how<br />

it can be measured. A GIS tool will be developed.<br />

Organisations:<br />

• Departement <strong>of</strong> Geography<br />

<strong>Research</strong>ers:<br />

• Philippe De Maeyer<br />

GINI - Growing Inequalities Impacts.<br />

University <strong>of</strong> Antwerp<br />

Abstract: Strategic objective:<br />

A major improvement in the understanding <strong>of</strong> changing inequalities and their impacts in the various countries <strong>of</strong> the European Union in comparison<br />

to other developed countries, including a longer-term perspective and with due attention paid to the impact on society as a whole<br />

Organisations:<br />

• Herman Deleeck Centre for Social Policy<br />

<strong>Research</strong>ers:<br />

• Ive Marx<br />

• Gerlinde Verbist<br />

• Bea Cantillon<br />

Record <strong>of</strong> fees and compensations: judicial DNA-research<br />

Universiteit Hasselt<br />

Abstract: This project represents a formal service agreement between the parties BIOMED (research institute at Hasselt University), and on the<br />

other hand, 'het Gerecht van Turnhout'. BIOMED provides 'het Gerecht van Turnhout' research results on the judicial DNA-research under the<br />

conditions as stipulated in the present contract.<br />

The work covers all states <strong>of</strong> the month february 2010<br />

Organisations:<br />

• Immunology - Biochemistry<br />

• Biomedical <strong>Research</strong> Institute<br />

<strong>Research</strong>ers:<br />

• Luc MICHIELS<br />

Hydrolysis <strong>of</strong> biopolymers by enzymes immobilized on membranes and its integration into a membrane reactor.

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