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Result #
Ref N.
Chemical Form
MW%
Appendix 6.1 Mammalian Toxicity Data Extracted for Wildlife Toxicity Reference Value (TRV)
Lead
Page 12 of 12
Ref Exposure Effects Conversion to mg/kg bw/day
Test Species
# of Conc/ Doses
Conc/ Doses
Conc/Dose Units
Wet Weight Reported?
Percent Moisture
Application Frequency
Method of Analyses
Route of Exposure
Exposure Duration
Duration Units
Age
Age Units
Lifestage
Sex
Control Type
Effect Type
Effect Measure
Response Site
Study NOAEL
Study LOAEL
Body Weight Reported?
Body Weight in kg
Ingestion Rate Reported?
Ingestion Rate in kg or L/day
NOAEL Dose (mg/kg/day)
Result Data Evaluation Score
575 2910 Tian et al., 1995 Lead acetate 54.61 Rat (Rattus norvegicus ) 2 0/0.2 % in water N DLY U DR 14 d 30 d JV F C REP Other PY 0.200 N 0.35 N 0.03849 120 10 5 5 5 5 10 4 10 10 4 68
576 2729 Kawamoto,1984 Lead acetate 100 Rat (Rattus norvegicus ) 2 0/1090 ug/g N ADL U DR 20 d NR NR JV F C REP Other PY 1090 N 0.302 N 0.0337 122 10 5 5 5 5 10 4 10 10 4 68
577 14749 Maljkovic et al, 1988 Lead acetate 100 Rat (Rattus norvegicus ) 5 0/1500/3500/5500/7500 mg/L N ADL U DR 35 d NR NR LC F C REP Other PY 1500 N 0.32 N 0.0355 166 10 5 5 5 5 10 4 10 10 4 68
578 14813 Carroll et al, 1977 Lead acetate 100 Mouse (Mus musculus ) 4 0/2/5/10 mg/ml N DLY U DR 30 d NR NR LC F C REP Other PY 2.00 Y 0.035 N 0.0048 277 10 5 5 5 6 10 4 10 10 4 69
579 2615 Epstein et al., 1999 Lead acetate 54.61 Mouse (Mus musculus ) 2 0/10 mg/ml N NR U DR 5 d NR NR GE F C REP Other PY 10.0 N 0.0325 N 0.00453 762 10 5 5 5 5 10 4 10 10 4 68
580 2615 Epstein et al., 1999 Lead acetate 54.61 Mouse (Mus musculus ) 2 0/10 mg/ml N NR U DR 24 d NR NR GE F C REP Other PY 10.0 N 0.0325 N 0.00453 762 10 5 5 5 5 10 4 10 10 4 68
581 2510 Alfano et al., 1982 Lead carbonate 77.55 Rat (Rattus norvegicus ) 2 0/4.0 % in diet N NR U FD 26 d NR NR LC F C REP Other PY 4.00 N 0.35 N 0.02899 2570 10 10 5 10 5 10 4 10 10 4 78
582 2512 Alfano et al., 1983 Lead carbonate 77.55 Rat (Rattus norvegicus) 2 0/4 % in diet N NR U FD 115 d NR NR LC F C REP Other PY 4.00 N 0.35 N 0.02899 2570 10 10 5 10 5 10 4 10 10 4 78
583 2814 Petit and Le Boutillier 1979 Lead carbonate 77.55 Rat (Rattus norvegicus ) 2 0/4 % in diet N ADL U FD 24 d NR NR LC F C REP Other PY 4.00 N 0.35 N 0.02899 2570 10 10 5 10 5 10 4 10 10 4 78
584 2740 Krigman et al. 1975 Lead carbonate 77.55 Rat (Rattus norvegicus ) 2 0/4 % in diet Y ADL U FD 25 d NR NR LC F C REP Other PY 4.00 N 0.35 N 0.02899 2700 10 10 5 10 5 10 4 10 10 4 78
585 2811 Pentschew and Garro 1966 Lead carbonate 77.55 Rat (Rattus norvegicus ) 2 0/4.0 % in diet NR NR M FD 27 d NR NR LC F C REP Other PY 4.5 N 0.248 N 0.02184 2840 10 10 10 5 5 10 4 10 10 4 78
The abbreviations and definitions used in coding data are provided in Attachment 4-3 of the Eco-SSL Guidance (U.S.EPA, 2003).
Eco-SSL for Lead March 2005
LOAEL Dose (mg/kg/day)
Data Source
Dose Route
Test Concentrations
Chemical form
Dose Quantification
Endpoint
Dose Range
Statistical Power
Exposure Duration
Test Conditions
Total