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Research resources<br />

13 + 1*- HIV/AIDS (see Global Fund below)<br />

12 + 1*- Malaria (see Global Fund below)<br />

8 Health policies <strong>and</strong> systems<br />

7 Chagas’, leishmaniasis, trypanosomiasis, lymphatic<br />

filariasis – individually or in combination with each o<strong>the</strong>r<br />

6 Microbicides<br />

5 + 1* Tuberculosis (see Global Fund below)<br />

5 Vaccines of <strong>the</strong> poor<br />

4 Onchocerciasis <strong>and</strong>/or trachoma<br />

3 Micronutrients/Vitamin A<br />

3 Reproductive <strong>health</strong><br />

2 Dengue<br />

1 Communicable diseases – prevention through h<strong>and</strong><br />

washing with soap<br />

1* The Global Fund <strong>to</strong> Fight AIDS, Tuberculosis <strong>and</strong> Malaria<br />

1 Guinea worm<br />

1 Hookworm<br />

1 Lassa fever<br />

1 Leprosy<br />

1 Meningitis<br />

1 Polio<br />

1 Schis<strong>to</strong>somiasis<br />

1 Tetanus<br />

Source: Extracted from data found on <strong>the</strong> website for Initiative on Public Private<br />

Partnerships for Health, www.ippph.org, accessed 1-8 February 2006.<br />

Table 1: Number of partnerships with associated disease or issue<br />

3. Advocacy <strong>and</strong> policy. The third type of PPP concentrates<br />

on <strong>health</strong> policies <strong>and</strong> systems <strong>and</strong> advocacy. Most of<br />

<strong>the</strong> partnerships that fall in this advocacy <strong>and</strong> policy<br />

category however, also have some technical, access, or<br />

product development component as well for example,<br />

GAVI, Drugs <strong>and</strong> Neglected Diseases inititative (DNDi),<br />

Global Alliance for Improved Nutrition (GAIN), SIGN.<br />

Of <strong>the</strong> 78 active partnerships, <strong>the</strong> number of partnerships<br />

that focus on certain diseases or <strong>health</strong> policy issues is set out<br />

in Table 1. Categorization is not an exact science as<br />

partnerships may deal in any combination with product<br />

distribution, product development, <strong>and</strong>/or policy <strong>and</strong> <strong>health</strong><br />

systems issues between or among various diseases.<br />

Twenty-four public-private partnerships devote <strong>the</strong> majority<br />

of <strong>the</strong>ir efforts <strong>to</strong> developing medicines, vaccines, or<br />

diagnostics for diseases of developing countries including<br />

malaria, tuberculosis, HIV, leishmaniasis, <strong>and</strong> o<strong>the</strong>rs<br />

collectively referred <strong>to</strong> as “neglected diseases” (see Figure 2).<br />

Of <strong>the</strong> 24 PPPs for Product Development, 9 are devoted <strong>to</strong><br />

developing medicines <strong>and</strong>/or microbicides, 11 are committed<br />

<strong>to</strong> vaccine development, one is focused on diagnostic<br />

products, <strong>and</strong> three are involved with <strong>the</strong> development of a<br />

combination of medicines, vaccines <strong>and</strong>/or diagnostics. Five<br />

partnerships focus exclusively on reproductive <strong>health</strong> issues,<br />

four focus on malaria <strong>and</strong> two are committed <strong>to</strong> tuberculosis<br />

<strong>and</strong> HIV/AIDS respectively.<br />

Current situation with regard <strong>to</strong> PPPs for<br />

<strong>health</strong><br />

There were early perceptions <strong>and</strong> criticism that <strong>the</strong>se<br />

partnerships would lead <strong>to</strong> dis<strong>to</strong>rtion of national policies <strong>and</strong><br />

public <strong>health</strong> funding, parallel systems of drugs supply etc.<br />

However <strong>the</strong>se have been largely dispelled through<br />

programme evaluation <strong>and</strong> assessments which have shown a<br />

positive impact – although it is true <strong>to</strong> say that many of <strong>the</strong><br />

partnerships are still <strong>to</strong>o young <strong>to</strong> measure real impact.<br />

The raised awareness <strong>and</strong> stimulation of research <strong>and</strong><br />

development on drugs/prevention for neglected diseases has<br />

certainly changed <strong>the</strong> field over <strong>the</strong> last seven years. There is<br />

now a very crowded l<strong>and</strong>scape of PPPs, particularly in a few<br />

sec<strong>to</strong>rs as illustrated by Figure 3, which has changed<br />

considerably since <strong>the</strong> early partnerships were formed. Most<br />

of <strong>the</strong> neglected diseases are addressed by at least one PPP<br />

providing research <strong>and</strong> development, drugs <strong>and</strong> technical<br />

support <strong>and</strong>/or some funding.<br />

The recent analysis of drug development for neglected<br />

5<br />

4<br />

3<br />

2<br />

1<br />

0<br />

1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004<br />

1984–2004<br />

Figure 2: Number of Public-Private Partnerships for Product Development created by year from 1984 <strong>to</strong> 2004<br />

Extracted from partnership database found on website for Initiative on<br />

Public-Private Partnerships for Health, www.ippph.org, accessed various<br />

times December 2004.<br />

134 ✜ Global Forum Update on Research for Health Volume 4

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