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Innovation<br />

The role of Knowledge<br />

Translation in bridging<br />

<strong>the</strong> “know-do gap”<br />

Article by Ariel Pablos-Méndez (pictured) <strong>and</strong> Ramesh Shademani<br />

During <strong>the</strong> 20th century, knowledge in all its forms<br />

contributed <strong>to</strong> unprecedented global <strong>health</strong> gains 2 . Yet<br />

ill-<strong>health</strong> <strong>and</strong> premature deaths from preventable<br />

causes persist, especially among poor children <strong>and</strong> women,<br />

in spite of available cost-effective interventions 2,3 . Studies<br />

show that more than half of <strong>the</strong> deaths <strong>to</strong> children under five<br />

years old can be prevented by <strong>the</strong> use of available<br />

interventions 2,3,4 . Such studies indicate that most of <strong>the</strong><br />

burden of premature death <strong>and</strong> illness among <strong>the</strong> poor is due<br />

<strong>to</strong> problems for which solutions are known <strong>and</strong> prevention is<br />

possible. Even in war-ravaged countries, most deaths are<br />

from easily preventable <strong>and</strong> treatable illness ra<strong>the</strong>r than<br />

violence 5 . The achievement of <strong>the</strong> <strong>health</strong> Millennium<br />

Development Goals (MDGs) in many developing countries is<br />

questionable. The obvious “know-do gap” was recognized by<br />

<strong>the</strong> Mexico Ministerial Summit on Health Research in<br />

November 2004 6 <strong>and</strong> by <strong>the</strong> 58th World Health Assembly in<br />

May 2005 as a major obstacle <strong>to</strong> <strong>the</strong> attainment of <strong>the</strong><br />

Millennium Development Goals.<br />

Bridging <strong>the</strong> know-do gap is <strong>the</strong> foremost challenge <strong>and</strong><br />

opportunity for public <strong>health</strong> in <strong>the</strong> 21st century. New<br />

initiatives <strong>and</strong> platforms <strong>to</strong> streng<strong>the</strong>n specific aspects of <strong>the</strong><br />

<strong>health</strong> systems such as <strong>health</strong> information systems, human<br />

resources, <strong>and</strong> equitable access <strong>and</strong> coverage have emerged.<br />

Knowledge <strong>and</strong> its links <strong>to</strong> action is ano<strong>the</strong>r platform for<br />

<strong>health</strong> system streng<strong>the</strong>ning.<br />

Evidence <strong>and</strong> knowledge for problemsolving<br />

There is widespread agreement that policy <strong>and</strong> practice<br />

should be informed by <strong>the</strong> best available evidence that is<br />

applicable in a given setting. However, <strong>the</strong>re is debate on<br />

what constitutes evidence <strong>and</strong> how <strong>to</strong> harness it in practice,<br />

<strong>and</strong> whe<strong>the</strong>r it is sufficient <strong>to</strong> bring about sustainable change<br />

in complex <strong>social</strong> settings. The goal of traditional researchers,<br />

conditioned by funding <strong>and</strong> tenure systems, is often <strong>to</strong> get<br />

published in a respected medical journal – assuming <strong>the</strong>ir<br />

findings will be translated in<strong>to</strong> practice by somebody else at<br />

some point. In addition, learning about effective development<br />

projects taking place in poor countries is sometimes hindered<br />

by <strong>the</strong> lack of general knowledge of what works <strong>and</strong> how 8 . A<br />

shift from “moving” evidence <strong>to</strong> solving problems is overdue.<br />

The contribution of knowledge <strong>to</strong> <strong>health</strong> gains has been<br />

dominated by consideration of benefits of science <strong>and</strong><br />

technology, neglecting <strong>to</strong> exploit <strong>and</strong> use o<strong>the</strong>r valid sources<br />

of knowledge: knowledge from practice <strong>and</strong> <strong>the</strong> sharing <strong>and</strong><br />

replication of people’s experience. The tacit dimension of<br />

knowledge, <strong>the</strong> <strong>social</strong> context of knowledge, <strong>and</strong> <strong>the</strong> various<br />

knowledge-creating mechanisms in practice are gaining<br />

importance, paradoxically, following <strong>the</strong> ICT revolution which<br />

mainly h<strong>and</strong>les increasing volumes of disembodied explicit<br />

(i.e. codified) information 9 . A strategic approach <strong>to</strong> creating<br />

<strong>and</strong> promoting evidence from practice in priority areas should<br />

contribute <strong>to</strong> bridging <strong>the</strong> know-do gap.<br />

Knowledge has been recognized by economists as <strong>the</strong> most<br />

important fac<strong>to</strong>r of production in <strong>the</strong> new economy. A<br />

knowledge economy (including <strong>health</strong> sec<strong>to</strong>r) is “one in<br />

which <strong>the</strong> generation <strong>and</strong> exploitation of knowledge has come<br />

<strong>to</strong> play a predominant part in <strong>the</strong> creation of wealth. It is not<br />

simply about pushing back <strong>the</strong> frontiers of knowledge; it is<br />

also about <strong>the</strong> more effective use <strong>and</strong> exploitation of all types<br />

of knowledge” 10 .<br />

The golden era of modern research, which started after <strong>the</strong><br />

Second World War, was a period in which research findings<br />

outside strategic government projects were published 11 <strong>and</strong><br />

passive diffusion followed. The 1970s saw <strong>the</strong> birth of<br />

evidence-based medicine which <strong>to</strong>ok a push strategy with<br />

both active dissemination of practice guidelines <strong>and</strong><br />

education for <strong>the</strong>ir local interpretation <strong>and</strong> adaptation;<br />

technology assessment also emerged at a time when private<br />

industry <strong>to</strong>ok over most product R&D. Conceptual<br />

frameworks derived from <strong>the</strong> <strong>social</strong> <strong>the</strong>ory of diffusion of<br />

innovation at <strong>the</strong> time included Research Transfer <strong>and</strong><br />

Research Utilization; <strong>the</strong> private sec<strong>to</strong>r developed value chain<br />

models, <strong>and</strong> marketing strategies. The success of evidencebased<br />

medicine, however, plateaued in <strong>the</strong> 1990s <strong>and</strong> <strong>the</strong><br />

new millennium dawned with fresh thinking on this old<br />

frontier. In Canada, for example, institutions were reorganized<br />

or created, crafting <strong>the</strong> term Knowledge Translation <strong>and</strong><br />

emphasizing linkage <strong>and</strong> exchange models 12 .<br />

104 ✜ Global Forum Update on Research for Health Volume 4

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