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Innovation<br />

Towards <strong>the</strong> development of a<br />

Health Innovation Strategy for<br />

South Africa<br />

Article by Glaudina Loots<br />

South Africa is currently at a significant set of crossroads<br />

due <strong>to</strong> <strong>the</strong> great need for <strong>health</strong> innovation <strong>to</strong> combat<br />

<strong>the</strong> tremendous <strong>health</strong> challenges in our diverse<br />

society. The <strong>health</strong> needs should be addressed in such a way<br />

that <strong>the</strong> serious inequalities of our society at large are<br />

encompassed <strong>and</strong> negated. This means that <strong>the</strong> medication<br />

that is developed should be appropriate, accessible <strong>and</strong><br />

culturally acceptable <strong>to</strong> <strong>the</strong> population. This issue <strong>the</strong>n needs<br />

<strong>to</strong> take in<strong>to</strong> account various major challenges such as<br />

appropriate <strong>health</strong> medication, <strong>health</strong> infrastructure <strong>and</strong> also<br />

appropriate needs-oriented research. This article will give a<br />

broad <strong>and</strong> brief overview of <strong>the</strong> progress <strong>to</strong>wards <strong>the</strong><br />

establishment of a Health Innovation Strategy for South Africa<br />

from <strong>the</strong> perspective of <strong>the</strong> South African national government<br />

Department of Science <strong>and</strong> Technology.<br />

The meaning <strong>and</strong> need for a Health<br />

Innovation Strategy<br />

The continuous need for new drugs, vaccine <strong>and</strong> diagnostics<br />

<strong>and</strong> new processes in engineering <strong>and</strong> manufacturing, as well<br />

as new approaches <strong>to</strong> <strong>health</strong> systems <strong>and</strong> services within<br />

developing countries 1 is driving <strong>the</strong> need for <strong>the</strong> development<br />

of <strong>health</strong> innovation strategies. Within this context <strong>the</strong>re is a<br />

need for an overarching framework that can facilitate this<br />

process – this is where an appropriate Health Innovation<br />

Strategy fits in<strong>to</strong> <strong>the</strong> picture.<br />

An area of global concern is that only 10% of <strong>the</strong> global<br />

<strong>health</strong> research <strong>and</strong> development budget is being spent on<br />

90% of <strong>the</strong> global <strong>health</strong> problems 2 . This unequal flow of<br />

resources has since been referred <strong>to</strong> as <strong>the</strong> “10/90 gap”.<br />

Health in <strong>the</strong> developing countries is no longer <strong>the</strong> concern of<br />

<strong>the</strong> developed countries; however, <strong>the</strong>re is growing recognition<br />

internationally that <strong>the</strong> <strong>health</strong> of more than 80% of <strong>the</strong> world<br />

is a matter of concern <strong>to</strong> all who inhabit this world. One of <strong>the</strong><br />

crucial fac<strong>to</strong>rs responsible for this “10/90” gap is <strong>the</strong> lack of<br />

integration of <strong>health</strong> research in<strong>to</strong> national <strong>and</strong> international<br />

research systems.<br />

India, Brazil, China <strong>and</strong> South Africa are currently seen as<br />

<strong>the</strong> leading innovative developing countries. Of <strong>the</strong> four, South<br />

Africa’s Health Research <strong>and</strong> Development (R&D) budget<br />

as a percentage of public <strong>health</strong> expenditure is <strong>the</strong> lowest <strong>and</strong><br />

falls behind that of India <strong>and</strong> Brazil. For South Africa <strong>to</strong> be on<br />

par with <strong>the</strong> o<strong>the</strong>r three countries, a concerted effort needs <strong>to</strong><br />

be made <strong>to</strong> increase <strong>the</strong> government R&D expenditure.<br />

It is increasingly being recognized that <strong>health</strong> research exists<br />

within <strong>the</strong> broader context of research systems which, in turn,<br />

function within <strong>the</strong> specific socio-political <strong>and</strong> economic<br />

context of <strong>the</strong> relevant country 3 .<br />

Similarly, <strong>health</strong> innovation systems operate within a given<br />

country’s education, manufacturing, research <strong>and</strong><br />

development system – guided, naturally, by regula<strong>to</strong>ry<br />

systems, intellectual property policies <strong>and</strong> market forces,<br />

domestically <strong>and</strong> internationally.<br />

It is within this complex context that <strong>the</strong> South African<br />

government <strong>and</strong>, in particular, <strong>the</strong> Department of Science <strong>and</strong><br />

Technology, is engaged in establishing a national framework<br />

that will enable research, development <strong>and</strong> innovation.<br />

Research, development <strong>and</strong> innovation<br />

within <strong>the</strong> South African context<br />

The National Research <strong>and</strong> Development Strategy (2002) 4<br />

(NRDS) in South Africa was adopted by Parliament as a<br />

strategy geared <strong>to</strong>wards <strong>the</strong> establishment of <strong>the</strong> necessary<br />

enabling environment. The NRDS recognizes <strong>the</strong> complex<br />

interplay <strong>and</strong> <strong>the</strong> synergies that can be created through coordination<br />

between sec<strong>to</strong>r specific research systems <strong>and</strong> <strong>the</strong><br />

National System of Innovation that includes <strong>the</strong> universities,<br />

<strong>the</strong> various national science councils, government <strong>and</strong> <strong>the</strong><br />

private sec<strong>to</strong>r.<br />

The NRDS sees <strong>the</strong> Department of Science <strong>and</strong> Technology<br />

(DST) playing a strong role with regard <strong>to</strong> <strong>health</strong> research <strong>and</strong><br />

<strong>health</strong> technology in South Africa. Health-related research<br />

should soften <strong>the</strong> devastation caused by diseases.<br />

The NRDS recognizes that <strong>the</strong> following issues, although<br />

not exhaustive, should form <strong>the</strong> core of <strong>the</strong> <strong>health</strong> research<br />

effort:<br />

✜ Underst<strong>and</strong>ing <strong>the</strong> <strong>social</strong> impact of disease.<br />

✜ Creating an environment <strong>and</strong> technologies <strong>to</strong> reduce <strong>the</strong><br />

effect of poverty on <strong>the</strong> spread of disease.<br />

✜ Developing care <strong>and</strong> support strategies.<br />

✜ Underst<strong>and</strong>ing <strong>the</strong> challenges in providing access <strong>to</strong><br />

prevention <strong>and</strong> care <strong>measures</strong>.<br />

✜ Developing innovative preventative strategies.<br />

✜ Developing novel <strong>the</strong>rapeutic regimes, including <strong>the</strong><br />

utilization of indigenous knowledge.<br />

✜ Developing preventive <strong>and</strong> <strong>the</strong>rapeutic HIV/AIDS vaccines.<br />

076 ✜ Global Forum Update on Research for Health Volume 4

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