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A Guide to Primary Care of People with HIV/AIDS - Canadian Public ...

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A <strong>Guide</strong> <strong>to</strong> <strong>Primary</strong> <strong>Care</strong> <strong>of</strong> <strong>People</strong> <strong>with</strong> <strong>HIV</strong>/<strong>AIDS</strong><br />

Chapter 11: Postexposure Prophylaxis<br />

11<br />

SUGGESTED RESOURCES<br />

<strong>Guide</strong>lines for the Management <strong>of</strong> Occupational<br />

Exposures <strong>to</strong> HBV, HCV, and <strong>HIV</strong> and<br />

Recommendations for Postexposure Prophylaxis.<br />

Available at http://aidsinfo.nih.gov/guidelines/.<br />

PEP Steps–a pocket summary <strong>of</strong> the 2001 PEP<br />

<strong>Guide</strong>lines. Mountain Plains <strong>AIDS</strong> Education and<br />

Training Center. Available at http://www.uchsc.edu/<br />

mpaetc/hivresources.htm or by telephone at 303-<br />

315-2516.<br />

Practice recommendations for health-care facilities<br />

implementing the U.S. <strong>Public</strong> Health Service<br />

guidelines for management <strong>of</strong> occupational<br />

exposures <strong>to</strong> bloodborne pathogens. MMWR<br />

2001;50(RR-11):43-44. Available at http:<br />

//www.cdc.gov/mmwr/preview/mmwrhtml/<br />

rr5011a2.htm.<br />

Recommendations for the Use <strong>of</strong> Antiretroviral<br />

Drugs in Pregnant <strong>HIV</strong>-1 Infected Women for<br />

Maternal Health and Interventions <strong>to</strong> Reduce<br />

Perinatal <strong>HIV</strong>-1 Transmission in the United States.<br />

Available at http://www.hivatis.org.<br />

WEBSITES<br />

Food and Drug Administration: http://www.fda.gov.<br />

Accessed 1/04.<br />

Hepatitis information: http://www.cdc.gov/hepatitis.<br />

Accessed 1/04.<br />

<strong>HIV</strong> PEP registry, for nonoccupational exposures:<br />

http://www.hivpepregistry.org. Accessed 1/04.<br />

National Rape, Abuse, & Incest National Network:<br />

http://www.rainn.org/. Accessed 1/04.<br />

Needlestick website, a web-based expert system<br />

<strong>to</strong> help providers manage and document<br />

occupational exposures <strong>to</strong> blood and bodily fluids:<br />

http://www.needlestick.mednet.ucla.edu.<br />

Accessed 1/04.<br />

New York State Department <strong>of</strong> Health<br />

<strong>AIDS</strong> Institute, PEP guidelines: http://<br />

www.hivguidelines.org. Accessed 1/04.<br />

STD/<strong>HIV</strong> Prevention Training Centers (PTCs): http:<br />

//depts.washing<strong>to</strong>n.edu/nnptc Accessed 10/03.<br />

Contact State and local health departments for<br />

additional information.<br />

TELEPHONE<br />

National Rape Crisis Hotline: 1-800-658-HOPE.<br />

National Clinicians’ Post-Exposure Prophylaxis<br />

Hotline (PEPline), expert consultation for providers<br />

on occupational exposures <strong>to</strong> bloodborne<br />

pathogens: 1-888-<strong>HIV</strong>-4911 (1-888-448-4911<br />

or http://www.ucsf.edu/hivcntr/resources/pep.<br />

Accessed 1/04.<br />

Warmline: National <strong>HIV</strong> telephone consultation<br />

service: 1-800-933-3413<br />

REFERENCES<br />

Bell DM. Occupational risk <strong>of</strong> human<br />

immunodeficiency virus infection in<br />

healthcare workers: an overview. Am J Med.<br />

1997;102(suppl 5B):9-15.<br />

Cardo DM, Culver DH, Ciesielski CA, et al.<br />

A case-control study <strong>of</strong> <strong>HIV</strong> seroconversion<br />

in health care workers after percutaneous<br />

exposure. N Engl J Med. 1997;337:1485-1490.<br />

Centers for Disease Control and Prevention.<br />

Updated guidelines for the management <strong>of</strong><br />

occupational exposures <strong>to</strong> HBV, HCV, and<br />

<strong>HIV</strong> and recommendations for postexposure<br />

prophylaxis. <strong>Public</strong> Health Service. MMWR.<br />

2001:50(RR11):1-42.<br />

Centers for Disease Control and Prevention.<br />

Management <strong>of</strong> possible sexual, injectingdrug-use,<br />

or other nonoccupational<br />

exposure <strong>to</strong> <strong>HIV</strong>, including considerations<br />

related <strong>to</strong> antiretroviral therapy. <strong>Public</strong><br />

Health Service Statement. MMWR. 1998;<br />

47(RR-17):1-14.<br />

Centers for Disease Control and Prevention.<br />

Recommendations for the prevention and<br />

control <strong>of</strong> hepatitis C virus (HCV) infection<br />

and HCV-related chronic disease. MMWR.<br />

1998; 47(RR-19):1-39.<br />

Gerberding JL. Occupational exposure <strong>to</strong><br />

<strong>HIV</strong> in health care settings. N Engl J Med.<br />

2003;348:826-833.<br />

New York State Department <strong>of</strong> Health <strong>AIDS</strong><br />

Institute. <strong>HIV</strong> PEP <strong>Guide</strong>lines. Available at<br />

http://www.hivguidelines.org Accessed 1/04.<br />

Mayer KH, Anderson DJ. Heterosexual <strong>HIV</strong><br />

transmission. Infect Agents Dis. 1995;4:273-284.<br />

Stephenson J. PEP talk: treating<br />

nonoccupational <strong>HIV</strong> exposure. JAMA.<br />

2003;289:287-288.<br />

Werner BG, Grady GF. Accidental hepatitis-Bsurface-antigen-positive<br />

inoculations: use <strong>of</strong><br />

e antigen <strong>to</strong> estimate infectivity. Ann Intern<br />

Med. 1982;97:367-369.<br />

94<br />

U.S. Department <strong>of</strong> Health and Human Services, Health Resources and Services Administration, <strong>HIV</strong>/<strong>AIDS</strong> Bureau

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