Biosafety Manual PDF - Lawrence Berkeley National Laboratory

More documents

Recommendations

Info

Biosafety Manual IBC-approved version (May 18, 2010) 2.0 Starting and Conducting Work Safely This section and Table 1 provide a simplified list to assist supervisors, work leads, and principal investigators in getting work with biological materials planned, assessed, authorized, and conducted. Specific sections of this manual and PUB-3000, Chapter 26 (Biosafety) should be consulted for additional information and requirements: Table 1 Guidance for Starting and Conducting Work Guidance Work Operation Planning, Risk Assessment, Authorization, and Control Complete and maintain a Biosafety Work Authorization (i.e., Biological Use Authorization (BUA), Biological Use Registration (BUR), Biological Use Notification (BUN), or Exposure Control Plan (ECP)) and any other required authorization. The Biosafety Work Authorization documents the work, risks, and controls. Implement the controls listed in the authorization. • Complete the Biological Use Application Form for research with biological materials. o Submit the application form to the Environment, Health, and Safety (EH&S) Biosafety Office (BWKing@lbl.gov and VMXian@lbl.gov) for review by the Institutional Biosafety Committee (IBC) and/or Biosafety Officer. o Resolve any review comments. o Work with the Biosafety Office to get the completed Biosafety Work Authorization signed and authorized. The Biosafety Office will load the authorization into the Biosafety Authorization System (BAS). o Ensure workers are familiar with the authorization document, understand the required controls, and are trained. o Ensure the containment controls noted in the authorization document are implemented. Also implement applicable controls noted in PUB- 3000, Chapter 26 (Biosafety) and the Biosafety Manual. Standard Laboratory Biosafety Level (BL) 1 and BL2 criteria are summarized in Appendix C. o Update personnel, biosafety training, and work locations as needed in the BAS. o Update and submit for review the authorization document to the Biosafety Office prior to the target renewal date. Ensure authorization document is re-authorized as needed. LBNL Policy Section Biosafety Manual, Section 5.1 PUB-3000, Section 26.8.2 PUB-3000, Section 26.8.2 PUB-3000, Table 26-6 Biosafety Manual, Section 5.2 Biosafety Manual, Sections 4.0 and 5.0 PUB-3000, Table 26-6 Printed copies are not official versions of this manual. Before using the printed copy, verify that it is the most current version. 10
Biosafety Manual IBC-approved version (May 18, 2010) Guidance • Complete and submit an Exposure Control Plan for nonresearch work that involves exposure to bloodborne pathogen materials. • Complete and get approval on any required protocols for research involving vertebrate animals or human subjects (including human-derived data or human-derived tissues) via the Animal Welfare and Research Committee (AWRC) or Human Subjects Committee (HSC), respectively. Worker Authorization and Control Identify the work, hazards, and controls for each worker or subcontractor and ensure the controls are implemented. Ensure each worker completes: • A Job Hazards Analysis (JHA) or Subcontractor Job Hazards Analysis and Work Authorization (SJHAWA). • Required controls on their JHA or SJHAWA, including required training courses. • Applicable job and operation-specific instruction related to biosafety. • Any required medical surveillance noted on their JHA, SJHAWA, or work authorization document. Assessment and Improvement • Assess and continuously improve the biosafety of the work. • Conduct periodic biosafety assessments of the operation as specified in the Division Self-Assessment Program, including assessment of the safety of tasks being performed, safety of the work area and equipment, training, and compliance with the Biosafety Work Authorization and standards. • Participate in periodic Biosafety or other Environment, Safety, and Health (ES&H) Technical Assurance Program (TAP) assessments of the operation, when scheduled. • Continuously improve the biosafety of the work, including tracking and correcting deficiencies when required in the Corrective Action Tracking System (CATS). Whom to Call Refer to the Whom to Call list in Section 1.6. LBNL Policy Section PUB-3000, Section 26.8.3 PUB-3000, Chapter 22 Biosafety Manual, Section 5.2.1 Biosafety Manual, Section 5.2.2 Biosafety Manual, Section 5.2.3 Biosafety Manual, Section 5.3 PUB-3000, Section 26.9 PUB-3000, Section 26.9 PUB-3000, Section 26.9 PUB-3000, Section 26.9 Biosafety Manual, Section 1.6 Printed copies are not official versions of this manual. Before using the printed copy, verify that it is the most current version. 11
Page 1 and 2: Biosafety Manual Lawrence Berkeley
Page 3 and 4: Biosafety Manual IBC-approved versi
Page 9: Biosafety Manual IBC-approved versi
Page 61 and 62:
Biosafety Manual IBC-approved versi
Page 63 and 64:
Page 65 and 66:
Page 67 and 68:
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
Page 75 and 76:
Page 77 and 78:
Page 79 and 80:
Page 81 and 82:
Page 83 and 84:
Page 85 and 86:
Page 87 and 88:
Page 89 and 90:
Page 91 and 92:
Page 93 and 94:
Page 95 and 96:
Page 97 and 98:
Page 99 and 100:
Page 101 and 102:
Page 103 and 104:
Page 105 and 106:
Page 107 and 108:
Page 109 and 110:
Page 111 and 112:
Page 113 and 114:
Page 115 and 116:
Page 117 and 118:
Page 119 and 120:
Page 121 and 122:
Page 123 and 124:
Page 125 and 126:
Page 127 and 128:
Page 129 and 130:
Page 131 and 132:
Page 133 and 134:
Page 135 and 136:
Page 137 and 138:
Page 139 and 140:
Page 141 and 142:
Page 143 and 144:
Page 145 and 146:
Page 147 and 148:
Page 149 and 150:
Page 151 and 152:
Page 153 and 154:
Page 155 and 156:
Page 157 and 158:
Page 159 and 160:
Page 161 and 162:
Page 163 and 164:
Page 165 and 166:
Page 167 and 168:
Page 169 and 170:
Page 171 and 172:
Page 173 and 174:
Page 175 and 176:
Page 177 and 178:
Page 179 and 180:
Page 181 and 182:
Page 183 and 184:
Page 185 and 186:
Page 187:
show all

Biosafety Manual PDF - Lawrence Berkeley National Laboratory

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?