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Extraction Technologies For Medicinal And Aromatic Plants - Unido

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EXTRACTION TECHNOLOGIES FOR MEDICINAL AND AROMATIC PLANTS<br />

Special care must be paid to closures and seals. SFE of MAPs<br />

is mostly an extraction operation from solid materials, which is carried out in<br />

batch or semibatch mode. Therefore, extraction vessels need to be pressurized,<br />

depressurized, opened, fi lled, and closed again several times per day.<br />

In order to ensure fast and safe operation procedures and reliable seals,<br />

gaskets like O-rings are useful and closure devices have been specifi cally<br />

designed. Again, the technology needed is already fully developed. We refer<br />

to chapter 4 of the book by Bertucco and Vetter for details. The book also<br />

describes the machinery for moving fl uids under pressure, i.e. pumps and<br />

compressors. We conclude that setting up a laboratory-scale apparatus with<br />

which to perform feasibility studies concerning the possibility of applying<br />

SFE to MAPs is not really an issue, and can be done with a relatively small<br />

capital cost.<br />

However, this does not mean that SFE of MAPs is in itself an<br />

economically convenient operation. An accurate evaluation of production<br />

costs, including both capital and utility costs, must be performed before<br />

scaling up a process whose technical feasibility has been demonstrated at<br />

the laboratory level. Costs are also discussed in the book by Bertucco and<br />

Vetter (chapter 8), but are only indicative. The reader should remember that<br />

capital costs have been steadily decreasing in the last years must be taken<br />

into account.<br />

10.5 SFE Applied to <strong>Medicinal</strong> and <strong>Aromatic</strong><br />

<strong>Plants</strong><br />

A large number of MAPs has been considered for possible<br />

extraction by supercritical CO2. The most recent developments suitable to<br />

have industrial relevance are listed in Table 2. These examples illustrate the<br />

great potential of SFE in this fi eld.<br />

Plant name<br />

(part used)<br />

Calendula<br />

offi cinalis<br />

(fl owers)<br />

Table 2: <strong>Medicinal</strong> and aromatic plants extracted by SFE<br />

Product(s) extracted Reference<br />

Oleoresin Campos et al., 2005, Experimental<br />

data and modeling the supercritical<br />

fl uid extraction of marigold (Calendula<br />

offi cinalis) oleoresin, J Supercritical<br />

Fluids, 34: 163-170<br />

Danielski et al., 2007, Marigold<br />

(Calendula offi cinalis L.) oleoresin:<br />

solubility in SC-CO2 and composition<br />

profi le, Chem Eng Proc, 46: 99–106<br />

177

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