Douglas J. Rhee, MD

(2) LeishmaniasisNote: Eyelid lesion can cause conjunctivitis. 1stibogluconate sodium Pentostam 20 Sb/kg/d IV or IM for 20–28 daysORmeglumine antimonate Glucantime 20 Sb/kg/d IV or IM for 20–28 daysNote: Pediatric dosing same for both medications.(3) Microsporidia (Encephalitozoon hellem , Nosema corneum )fumagillin Fumidil-B 2ORitraconazole 3Note: Infections by E. hellem have responded to above. No topical regimen exists for N. corneum; may need penetrating keratoplasty.(4) Pneumocystis carinii choroiditistrimethoprim /sulfamethoxazole Bactrim 20 mg/kg IV QD (of TMP component) × 21 daysORpentamidine 4 mg/kg IV QD × 21 daysNote: Seen with disseminated disease. Must include systemic evaluation for other sites of disease and immunocompromised status.Pediatric dosing is the same.Antiparasitic Agents 49