Douglas J. Rhee, MD

42A. TOPICALDrug Trade Concentration Usual Dose Notesacyclovir Zovirax Oint, 3% 5×/day For HSV keratitisCommercially available in USA but can be made bycompounding pharmaciesidoxuridine Herplex Soln, 0.1%, 1% Q5×/day For HSV keratitisOint, 0.5% No longer commercially produced in USA, but can beorder through compounding pharmaciestrifluridine Viroptic Soln, 1.0% 9×/day, for 7–10 days; probably Preferred first line agent for HSV keratitisas effective used5× daily For HSV conjunctivitisvidarabine Vira-A Oint, 3.0% 5×/day For HSV keratitisNo longer available commercially but can be made bycompounding pharmaciesNote: The compounds now longer available commercially can be obtained from Leiter’s Rx Ophthalmic Compounding Pharmacy, SanJose, CA.